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Commercially bred chicks with maternally derived antibody to avian infectious bronchitis virus (IBV) were hatched in isolated conditions and a number vaccinated within the first three weeks of life with live IBV strain H120. Humoral antibody responses were assayed by haemagglutination inhibition (HI) or neutralisation (SN) tests, and the degree of protection against challenge with the virulent Massachusetts M41 strain assessed on the basis of tracheal ciliary activity four days after challenge. Maternal antibody in unvaccinated chicks declined linearly with a mean half-life of five to six days based on both HI and SN tests; these chicks were protected against challenge until four weeks old. There was complete correlation between ciliary activity and histopathological findings, but little between protection and antibody titre. It was concluded that the optimum age for primary vaccination was about two weeks.
J H Darbyshire, and
R W Peters
September 1994,
The Veterinary record,
J H Darbyshire, and
R W Peters
April 1986,
American journal of veterinary research,
J H Darbyshire, and
R W Peters
September 2015,
Clinical and vaccine immunology : CVI,
J H Darbyshire, and
R W Peters
December 1978,
Veterinariia,
J H Darbyshire, and
R W Peters
September 1998,
The Korean journal of parasitology,
J H Darbyshire, and
R W Peters
May 1966,
Avian diseases,
J H Darbyshire, and
R W Peters
October 2011,
Avian pathology : journal of the W.V.P.A,
J H Darbyshire, and
R W Peters
January 1987,
Avian pathology : journal of the W.V.P.A,
J H Darbyshire, and
R W Peters
February 2005,
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi,
J H Darbyshire, and
R W Peters
January 2016,
Avian pathology : journal of the W.V.P.A,
