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Rat vas deferens has been shown to become supersensitive to alpha-adrenergic agonists on brief treatment with epinephrine (Epi-treatment). Epi-treatment increased the contractile response and the number of alpha-adrenoceptors in the tissue. The application of colchicine (2.5 mM) during Epi-treatment prevented the supersensitivity-like phenomena and increase in number of alpha-adrenoceptors. Vinblastine (10 microM) also counteracted the effect of Epi-treatment but cytochalasin B (100 microM) and strychnine (2.5 mM) did not. It is suggested that the supersensitivity-like phenomena induced in rat vas deferens by Epi-treatment were due to a change in microtubular components of the membrane.
F Hata, and
Y Noguchi, and
N Koda, and
Y Kihira, and
E Kondo, and
Y Ishikawa, and
H Ishida
November 1980,
The Journal of physiology,
F Hata, and
Y Noguchi, and
N Koda, and
Y Kihira, and
E Kondo, and
Y Ishikawa, and
H Ishida
June 1979,
The Journal of pharmacology and experimental therapeutics,
F Hata, and
Y Noguchi, and
N Koda, and
Y Kihira, and
E Kondo, and
Y Ishikawa, and
H Ishida
February 1978,
Nihon Heikatsukin Gakkai zasshi,
F Hata, and
Y Noguchi, and
N Koda, and
Y Kihira, and
E Kondo, and
Y Ishikawa, and
H Ishida
November 1969,
European journal of pharmacology,
F Hata, and
Y Noguchi, and
N Koda, and
Y Kihira, and
E Kondo, and
Y Ishikawa, and
H Ishida
May 1977,
European journal of pharmacology,
F Hata, and
Y Noguchi, and
N Koda, and
Y Kihira, and
E Kondo, and
Y Ishikawa, and
H Ishida
March 2009,
Autonomic neuroscience : basic & clinical,
F Hata, and
Y Noguchi, and
N Koda, and
Y Kihira, and
E Kondo, and
Y Ishikawa, and
H Ishida
June 1976,
Canadian journal of physiology and pharmacology,
F Hata, and
Y Noguchi, and
N Koda, and
Y Kihira, and
E Kondo, and
Y Ishikawa, and
H Ishida
August 1982,
European journal of pharmacology,
F Hata, and
Y Noguchi, and
N Koda, and
Y Kihira, and
E Kondo, and
Y Ishikawa, and
H Ishida
November 1968,
European journal of pharmacology,
F Hata, and
Y Noguchi, and
N Koda, and
Y Kihira, and
E Kondo, and
Y Ishikawa, and
H Ishida
June 1981,
Japanese journal of pharmacology,
