BIOMAT Database Logo BIOMAT Database Logo

[Natural interferon inducers: double-stranded RNA of killer plasmids of Saccharomyces cerevisiae]. 1985

A B Duzhak, and A N Kostomakha, and N N Lobova, and V F Podgornyĭ, and N N Nosik

Methods for isolation and purification of yeast double spiral RNA (dsRNA) are described. The most simple method includes reprecipitation of dsRNA in solutions of lithium chloride and its interphase distribution in the system of chloroform: isoamilic alcohol: water. Preparations with the content (w/w) of dsRNA from 30 to 90 per cent were obtained. They possess a high interferon-inducing activity and an antiviral effect on the experimental infection caused by the virus of mouse encephalomyocarditis.

UI MeSH Term Description Entries
D007369 Interferon Inducers Agents that promote the production and release of interferons. They include mitogens, lipopolysaccharides, and the synthetic polymers Poly A-U and Poly I-C. Viruses, bacteria, and protozoa have been also known to induce interferons. Inducers, Interferon
D007370 Interferon Type I Interferon secreted by leukocytes, fibroblasts, or lymphoblasts in response to viruses or interferon inducers other than mitogens, antigens, or allo-antigens. They include alpha- and beta-interferons (INTERFERON-ALPHA and INTERFERON-BETA). Interferons Type I,Type I Interferon,Type I Interferons,Interferon, Type I,Interferons, Type I
D010957 Plasmids Extrachromosomal, usually CIRCULAR DNA molecules that are self-replicating and transferable from one organism to another. They are found in a variety of bacterial, archaeal, fungal, algal, and plant species. They are used in GENETIC ENGINEERING as CLONING VECTORS. Episomes,Episome,Plasmid
D004686 Encephalomyocarditis virus The type species of CARDIOVIRUS causing encephalomyelitis and myocarditis in rodents, pigs, and monkeys. Infection in man has been reported with CNS involvement but without myocarditis. EMCV
D004769 Enterovirus Infections Diseases caused by ENTEROVIRUS. Infections, Enterovirus,Enterovirus Infection,Infection, Enterovirus
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012330 RNA, Double-Stranded RNA consisting of two strands as opposed to the more prevalent single-stranded RNA. Most of the double-stranded segments are formed from transcription of DNA by intramolecular base-pairing of inverted complementary sequences separated by a single-stranded loop. Some double-stranded segments of RNA are normal in all organisms. Double-Stranded RNA,Double Stranded RNA,RNA, Double Stranded
D012331 RNA, Fungal Ribonucleic acid in fungi having regulatory and catalytic roles as well as involvement in protein synthesis. Fungal RNA
D012441 Saccharomyces cerevisiae A species of the genus SACCHAROMYCES, family Saccharomycetaceae, order Saccharomycetales, known as "baker's" or "brewer's" yeast. The dried form is used as a dietary supplement. Baker's Yeast,Brewer's Yeast,Candida robusta,S. cerevisiae,Saccharomyces capensis,Saccharomyces italicus,Saccharomyces oviformis,Saccharomyces uvarum var. melibiosus,Yeast, Baker's,Yeast, Brewer's,Baker Yeast,S cerevisiae,Baker's Yeasts,Yeast, Baker
D051379 Mice The common name for the genus Mus. Mice, House,Mus,Mus musculus,Mice, Laboratory,Mouse,Mouse, House,Mouse, Laboratory,Mouse, Swiss,Mus domesticus,Mus musculus domesticus,Swiss Mice,House Mice,House Mouse,Laboratory Mice,Laboratory Mouse,Mice, Swiss,Swiss Mouse,domesticus, Mus musculus

Related Publications

A B Duzhak, and A N Kostomakha, and N N Lobova, and V F Podgornyĭ, and N N Nosik
K28, a unique double-stranded RNA killer virus of Saccharomyces cerevisiae.
September 1990, Molecular and cellular biology,
A B Duzhak, and A N Kostomakha, and N N Lobova, and V F Podgornyĭ, and N N Nosik
The killer double-stranded RNA plasmids of yeast.
July 1979, Plasmid,
A B Duzhak, and A N Kostomakha, and N N Lobova, and V F Podgornyĭ, and N N Nosik
Double-stranded RNA viruses of Saccharomyces cerevisiae.
March 1996, Microbiological reviews,
A B Duzhak, and A N Kostomakha, and N N Lobova, and V F Podgornyĭ, and N N Nosik
[Genetic polymorphism of double stranded RNA of Saccharomyces plasmids].
January 2009, Mikrobiologiia,
A B Duzhak, and A N Kostomakha, and N N Lobova, and V F Podgornyĭ, and N N Nosik
Virus-like particles and double stranded RNA from killer and non-killer strains of Saccharomyces cerevisiae.
January 1978, Microbios,
A B Duzhak, and A N Kostomakha, and N N Lobova, and V F Podgornyĭ, and N N Nosik
Double-stranded and single-stranded RNA viruses of Saccharomyces cerevisiae.
January 1992, Annual review of microbiology,
A B Duzhak, and A N Kostomakha, and N N Lobova, and V F Podgornyĭ, and N N Nosik
Toxicity of interferon inducers of the double stranded RNA type.
December 1969, Nature,
A B Duzhak, and A N Kostomakha, and N N Lobova, and V F Podgornyĭ, and N N Nosik
Killer of Saccharomyces cerevisiae: a double-stranded ribonucleic acid plasmid.
September 1976, Bacteriological reviews,
A B Duzhak, and A N Kostomakha, and N N Lobova, and V F Podgornyĭ, and N N Nosik
[Comparative analysis of the structure of double-stranded RNA from killer strains of Saccharomyces cerevisiae].
January 1988, Molekuliarnaia biologiia,
A B Duzhak, and A N Kostomakha, and N N Lobova, and V F Podgornyĭ, and N N Nosik
Overview of double-stranded RNA replication in Saccharomyces cerevisiae.
January 1986, Basic life sciences,
Copied contents to your clipboard!