-transparent.png){kind=logo}
Cytochemical and immunological studies were performed on "hairy" cells from 5 patients. The results, primarily the detection of surface immunoglobulins after incubation in immunoglobulin-free medium support the hypothesis that hairy cells are B-cells. Further parameters for B-cell lineage are the failing suppression of unspecific esterases by NaF, the presence of tartrate-resistant acid phosphatase and the absence of phagocytic capacity and glass adherence (skin window). A lysozyme could not be demonstrated. Of two patients with prolymphocytic leukemia one was characterized as T- and one as B-cell leukemia. Therefore, the prolymphocytic leukemia has to be discussed as intermediate form of ALL and CLL. In both patients the therapeutic results were discouraging with cytostatics (e. g. chlorambucil), splenectomy is considered as the treatment of choice.
K Abbrederis, and
G Michlmayr, and
F Schmalzl
June 1997,
Medizinische Klinik (Munich, Germany : 1983),
K Abbrederis, and
G Michlmayr, and
F Schmalzl
January 1983,
Revista de medicina interna, neurologe, psihiatrie, neurochirurgie, dermato-venerologie. Medicina interna,
K Abbrederis, and
G Michlmayr, and
F Schmalzl
January 1988,
Nouvelle revue francaise d'hematologie,
K Abbrederis, and
G Michlmayr, and
F Schmalzl
April 1986,
Cancer research,
K Abbrederis, and
G Michlmayr, and
F Schmalzl
December 1984,
Seminars in oncology,
K Abbrederis, and
G Michlmayr, and
F Schmalzl
January 1990,
Neoplasma,
K Abbrederis, and
G Michlmayr, and
F Schmalzl
March 2002,
Anales de medicina interna (Madrid, Spain : 1984),
K Abbrederis, and
G Michlmayr, and
F Schmalzl
December 1981,
Cancer,
K Abbrederis, and
G Michlmayr, and
F Schmalzl
January 1955,
Praxis,
K Abbrederis, and
G Michlmayr, and
F Schmalzl
December 1997,
Leukemia & lymphoma,
