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This study assessed the enhancement of immunocompetence by relaxation and social contact in 45 geriatric residents of independent-living facilities. Subjects were randomly assigned to one of three protocols: relaxation training, social contact, or no contact. Subjects in the relaxation and social-contact conditions were seen individually three times a week for a month. Blood samples and self-report data were obtained at baseline, at the end of the intervention, and at a 1-month follow-up. At the end of the intervention, the relaxation group showed a significant increase in natural killer cell activity, and significant decreases in antibody titers to Herpes simplex virus and self-rated distress; the other two groups showed nonsignificant changes. There was a general increase in the T-lymphocyte response to phytohemagglutinin stimulation at the end of the intervention, with greater change at lower mitogen concentrations. These data suggest that cellular immunocompetence may be enhanced by psychosocial interventions.
J K Kiecolt-Glaser, and
R Glaser, and
D Williger, and
J Stout, and
G Messick, and
S Sheppard, and
D Ricker, and
S C Romisher, and
W Briner, and
G Bonnell
July 1991,
Holistic nursing practice,
J K Kiecolt-Glaser, and
R Glaser, and
D Williger, and
J Stout, and
G Messick, and
S Sheppard, and
D Ricker, and
S C Romisher, and
W Briner, and
G Bonnell
November 1984,
Der Internist,
J K Kiecolt-Glaser, and
R Glaser, and
D Williger, and
J Stout, and
G Messick, and
S Sheppard, and
D Ricker, and
S C Romisher, and
W Briner, and
G Bonnell
July 1981,
Surgery,
J K Kiecolt-Glaser, and
R Glaser, and
D Williger, and
J Stout, and
G Messick, and
S Sheppard, and
D Ricker, and
S C Romisher, and
W Briner, and
G Bonnell
February 2000,
Vaccine,
J K Kiecolt-Glaser, and
R Glaser, and
D Williger, and
J Stout, and
G Messick, and
S Sheppard, and
D Ricker, and
S C Romisher, and
W Briner, and
G Bonnell
September 1992,
Journal of the American Geriatrics Society,
J K Kiecolt-Glaser, and
R Glaser, and
D Williger, and
J Stout, and
G Messick, and
S Sheppard, and
D Ricker, and
S C Romisher, and
W Briner, and
G Bonnell
November 2017,
Physical medicine and rehabilitation clinics of North America,
J K Kiecolt-Glaser, and
R Glaser, and
D Williger, and
J Stout, and
G Messick, and
S Sheppard, and
D Ricker, and
S C Romisher, and
W Briner, and
G Bonnell
February 1981,
Thymus,
J K Kiecolt-Glaser, and
R Glaser, and
D Williger, and
J Stout, and
G Messick, and
S Sheppard, and
D Ricker, and
S C Romisher, and
W Briner, and
G Bonnell
February 2001,
The journals of gerontology. Series A, Biological sciences and medical sciences,
J K Kiecolt-Glaser, and
R Glaser, and
D Williger, and
J Stout, and
G Messick, and
S Sheppard, and
D Ricker, and
S C Romisher, and
W Briner, and
G Bonnell
January 2000,
Zeitschrift fur Gerontologie und Geriatrie,
J K Kiecolt-Glaser, and
R Glaser, and
D Williger, and
J Stout, and
G Messick, and
S Sheppard, and
D Ricker, and
S C Romisher, and
W Briner, and
G Bonnell
January 1985,
Kango tenbo. The Japanese journal of nursing science,
