Serum oxytocin profiles in patients with repeated implantation failure during IVF cycles. 2018

Tingting Xia, and Qiuli Liu, and Qingjian Ye, and Weijie Xing, and Dong Wang, and Jie Li, and Zhi-Jun Zang
a Department of Infertility and Sexual Medicine , The Third Affiliated Hospital, Sun Yat-sen University , Guangzhou , China.

OBJECTIVE The objective of this study is to investigate the association between oxytocin (OT) levels and repeated implantation failure (RIF) during in vitro fertilization-embryo transfer (IVF-ET) cycles. METHODS Blood samples were collected from 108 women undergoing IVF-ET treatment at the following time points: gonadotrophin (Gn) administration day (Gn Day 0), hCG administration day (hCG Day 0), ET administration day (ET Day 0), and 5 d after ET (ET Day 5). Serum OT and steroid profiles were measured and compared among three groups: Group A included 38 women with a history of RIF, Group B included 41 women who became pregnant following the first fresh ET, and Group C included 29 women who did not become pregnant following the first fresh ET. RESULTS The OT levels of the three groups at different time points were not significantly different. Serum OT levels were significantly higher on hCG Day 0, ET Day 0, and ET Day 5 than on Gn Day 0, and they were significantly correlated with the estradiol concentration on ET Day 0. CONCLUSIONS RIF patients do not have elevated serum OT levels during IVF-ET cycles.

UI MeSH Term Description Entries
D007986 Luteinizing Hormone A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Luteinizing hormone regulates steroid production by the interstitial cells of the TESTIS and the OVARY. The preovulatory LUTEINIZING HORMONE surge in females induces OVULATION, and subsequent LUTEINIZATION of the follicle. LUTEINIZING HORMONE consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH and FSH), but the beta subunit is unique and confers its biological specificity. ICSH (Interstitial Cell Stimulating Hormone),Interstitial Cell-Stimulating Hormone,LH (Luteinizing Hormone),Lutropin,Luteoziman,Luteozyman,Hormone, Interstitial Cell-Stimulating,Hormone, Luteinizing,Interstitial Cell Stimulating Hormone
D010064 Embryo Implantation Endometrial implantation of EMBRYO, MAMMALIAN at the BLASTOCYST stage. Blastocyst Implantation,Decidual Cell Reaction,Implantation, Blastocyst,Nidation,Ovum Implantation,Blastocyst Implantations,Decidual Cell Reactions,Embryo Implantations,Implantation, Embryo,Implantation, Ovum,Implantations, Blastocyst,Implantations, Embryo,Implantations, Ovum,Nidations,Ovum Implantations
D010121 Oxytocin A nonapeptide hormone released from the neurohypophysis (PITUITARY GLAND, POSTERIOR). It differs from VASOPRESSIN by two amino acids at residues 3 and 8. Oxytocin acts on SMOOTH MUSCLE CELLS, such as causing UTERINE CONTRACTIONS and MILK EJECTION. Ocytocin,Pitocin,Syntocinon
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D004624 Embryo Transfer The transfer of mammalian embryos from an in vivo or in vitro environment to a suitable host to improve pregnancy or gestational outcome in human or animal. In human fertility treatment programs, preimplantation embryos ranging from the 4-cell stage to the blastocyst stage are transferred to the uterine cavity between 3-5 days after FERTILIZATION IN VITRO. Blastocyst Transfer,Tubal Embryo Transfer,Tubal Embryo Stage Transfer,Embryo Transfers,Transfer, Embryo,Transfers, Embryo
D004958 Estradiol The 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. Estradiol-17-beta is the most potent form of mammalian estrogenic steroids. 17 beta-Estradiol,Estradiol-17 beta,Oestradiol,17 beta-Oestradiol,Aerodiol,Delestrogen,Estrace,Estraderm TTS,Estradiol Anhydrous,Estradiol Hemihydrate,Estradiol Hemihydrate, (17 alpha)-Isomer,Estradiol Monohydrate,Estradiol Valerate,Estradiol Valeriante,Estradiol, (+-)-Isomer,Estradiol, (-)-Isomer,Estradiol, (16 alpha,17 alpha)-Isomer,Estradiol, (16 alpha,17 beta)-Isomer,Estradiol, (17-alpha)-Isomer,Estradiol, (8 alpha,17 beta)-(+-)-Isomer,Estradiol, (8 alpha,17 beta)-Isomer,Estradiol, (9 beta,17 alpha)-Isomer,Estradiol, (9 beta,17 beta)-Isomer,Estradiol, Monosodium Salt,Estradiol, Sodium Salt,Estradiol-17 alpha,Estradiol-17beta,Ovocyclin,Progynon-Depot,Progynova,Vivelle,17 beta Estradiol,17 beta Oestradiol,Estradiol 17 alpha,Estradiol 17 beta,Estradiol 17beta,Progynon Depot
D005260 Female Females
D005307 Fertilization in Vitro An assisted reproductive technique that includes the direct handling and manipulation of oocytes and sperm to achieve fertilization in vitro. Test-Tube Fertilization,Fertilizations in Vitro,In Vitro Fertilization,Test-Tube Babies,Babies, Test-Tube,Baby, Test-Tube,Fertilization, Test-Tube,Fertilizations, Test-Tube,In Vitro Fertilizations,Test Tube Babies,Test Tube Fertilization,Test-Tube Baby,Test-Tube Fertilizations
D005640 Follicle Stimulating Hormone A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Follicle-stimulating hormone stimulates GAMETOGENESIS and the supporting cells such as the ovarian GRANULOSA CELLS, the testicular SERTOLI CELLS, and LEYDIG CELLS. FSH consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity. FSH (Follicle Stimulating Hormone),Follicle-Stimulating Hormone,Follitropin
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

Tingting Xia, and Qiuli Liu, and Qingjian Ye, and Weijie Xing, and Dong Wang, and Jie Li, and Zhi-Jun Zang
May 2004, Fertility and sterility,
Tingting Xia, and Qiuli Liu, and Qingjian Ye, and Weijie Xing, and Dong Wang, and Jie Li, and Zhi-Jun Zang
April 2022, American journal of reproductive immunology (New York, N.Y. : 1989),
Tingting Xia, and Qiuli Liu, and Qingjian Ye, and Weijie Xing, and Dong Wang, and Jie Li, and Zhi-Jun Zang
January 2006, European journal of gynaecological oncology,
Tingting Xia, and Qiuli Liu, and Qingjian Ye, and Weijie Xing, and Dong Wang, and Jie Li, and Zhi-Jun Zang
April 2024, Clinical and experimental reproductive medicine,
Tingting Xia, and Qiuli Liu, and Qingjian Ye, and Weijie Xing, and Dong Wang, and Jie Li, and Zhi-Jun Zang
January 2012, Facts, views & vision in ObGyn,
Tingting Xia, and Qiuli Liu, and Qingjian Ye, and Weijie Xing, and Dong Wang, and Jie Li, and Zhi-Jun Zang
January 2008, Journal of assisted reproduction and genetics,
Tingting Xia, and Qiuli Liu, and Qingjian Ye, and Weijie Xing, and Dong Wang, and Jie Li, and Zhi-Jun Zang
April 2008, Journal of assisted reproduction and genetics,
Tingting Xia, and Qiuli Liu, and Qingjian Ye, and Weijie Xing, and Dong Wang, and Jie Li, and Zhi-Jun Zang
December 2006, Human reproduction (Oxford, England),
Tingting Xia, and Qiuli Liu, and Qingjian Ye, and Weijie Xing, and Dong Wang, and Jie Li, and Zhi-Jun Zang
December 2010, Journal of reproductive immunology,
Tingting Xia, and Qiuli Liu, and Qingjian Ye, and Weijie Xing, and Dong Wang, and Jie Li, and Zhi-Jun Zang
April 2016, Archives of gynecology and obstetrics,
Copied contents to your clipboard!