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IgA Nephropathy Complicated with X-linked Thrombocytopenia. 2018
Yuki Kakio, and
Haruhito Adam Uchida, and
Masashi Kitagawa, and
Yuka Arata, and
Ayako Kato, and
Akiko Inoue-Torii, and
Norikazu Hinamoto, and
Ayu Ogawa-Akiyama, and
Hitoshi Sugiyama, and
Jun Wada
Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan.
Renal involvement is occasionally observed in Wiskott-Aldrich syndrome (WAS) and X-linked thrombocytopenia (XLT). It has been reported that galactose-deficient IgA is a closely linked to IgA nephropathy (IgAN), suggesting that patients with XLT/WAS associated with reduced galactosylation on serum IgA are susceptible to IgAN. It is necessary to pay more attention to patients with IgAN due to the potential complication with XLT/WAS. We here present a patient of XLT complicated with mild IgAN who underwent tonsillectomy combined with steroid pulse therapy to achieve complete clinical remission.
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