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The activities of serum carboxypeptidases N (E.C. 3.4.17.3) and serum angiotensin-I-converting enzyme (E.C. 3.4.15.1) were spectrophotometrically measured in patients with hematological disorders and in histologically proven bronchogenic carcinomas. The enzyme activities have been compared with various laboratory parameters. Controls were healthy subjects. No significant sex differences of carboxypeptidases N and angiotensin-I-converting enzyme were found in the healthy controls or in the whole patients' group. The carboxypeptidases N were significantly elevated in patients with lung cancer (p less than 0.0001) compared to the healthy controls. The angiotensin-I-converting enzyme was significantly reduced (p less than 0.0001) in serum of patients with bronchogenic carcinoma. In responders to chemo- and/or radiotherapy, the carboxypeptidases decreased and the angiotensin-I-converting enzyme increased to normal enzyme values. In non-responders to these therapies no change in these enzymes could be observed.
H Schweisfurth, and
M Schmidt, and
E Brugger, and
L Maiwald, and
H Thiel
January 1992,
The Indian journal of chest diseases & allied sciences,
H Schweisfurth, and
M Schmidt, and
E Brugger, and
L Maiwald, and
H Thiel
October 1985,
The Journal of the Association of Physicians of India,
H Schweisfurth, and
M Schmidt, and
E Brugger, and
L Maiwald, and
H Thiel
November 1980,
Die Medizinische Welt,
H Schweisfurth, and
M Schmidt, and
E Brugger, and
L Maiwald, and
H Thiel
January 1985,
Clinical physiology and biochemistry,
H Schweisfurth, and
M Schmidt, and
E Brugger, and
L Maiwald, and
H Thiel
December 1978,
Nihon Kyobu Shikkan Gakkai zasshi,
H Schweisfurth, and
M Schmidt, and
E Brugger, and
L Maiwald, and
H Thiel
January 2008,
Hepato-gastroenterology,
H Schweisfurth, and
M Schmidt, and
E Brugger, and
L Maiwald, and
H Thiel
September 1976,
The American review of respiratory disease,
H Schweisfurth, and
M Schmidt, and
E Brugger, and
L Maiwald, and
H Thiel
January 1985,
Acta haematologica,
H Schweisfurth, and
M Schmidt, and
E Brugger, and
L Maiwald, and
H Thiel
February 1979,
Lancet (London, England),
H Schweisfurth, and
M Schmidt, and
E Brugger, and
L Maiwald, and
H Thiel
January 1986,
Enzyme,
