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A large Danish pedigree segregating for X-linked retinitis pigmentosa (RPX) (Warburg and Simonsen 1968) was restudied for linkage analysis. Using two markers, i.e. the DNA base sequence polymorphism presented by the probe L1.28 defining the chromosomal segment DXS7, and the C-banding heteromorphism (Xcen) (Friedrich 1982), we were able to localize the RPX gene in Xp close to the centromere rather precisely. The gene order could be deduced by three-point linkage analysis, and the gene distances were determined by pairwise analysis using the LIPED program (Ott 1974). Together with previously published data concerning the RPX:DXS7 linkage (Bhattacharya et al. 1984) a regional gene map is constructed. Xcen-11 cM-RPX-6 cM-DXS7.
U Friedrich, and
M Warburg, and
P Wieacker, and
T F Wienker, and
A Gal, and
H H Ropers
January 1983,
Human genetics,
U Friedrich, and
M Warburg, and
P Wieacker, and
T F Wienker, and
A Gal, and
H H Ropers
January 1983,
Human genetics,
U Friedrich, and
M Warburg, and
P Wieacker, and
T F Wienker, and
A Gal, and
H H Ropers
January 1985,
Human genetics,
U Friedrich, and
M Warburg, and
P Wieacker, and
T F Wienker, and
A Gal, and
H H Ropers
November 1982,
Nature,
U Friedrich, and
M Warburg, and
P Wieacker, and
T F Wienker, and
A Gal, and
H H Ropers
January 1972,
Humangenetik,
U Friedrich, and
M Warburg, and
P Wieacker, and
T F Wienker, and
A Gal, and
H H Ropers
January 1972,
Monographs in human genetics,
U Friedrich, and
M Warburg, and
P Wieacker, and
T F Wienker, and
A Gal, and
H H Ropers
January 1985,
Human genetics,
U Friedrich, and
M Warburg, and
P Wieacker, and
T F Wienker, and
A Gal, and
H H Ropers
May 1985,
The British journal of ophthalmology,
U Friedrich, and
M Warburg, and
P Wieacker, and
T F Wienker, and
A Gal, and
H H Ropers
May 1967,
Lancet (London, England),
U Friedrich, and
M Warburg, and
P Wieacker, and
T F Wienker, and
A Gal, and
H H Ropers
January 1983,
Transactions of the ophthalmological societies of the United Kingdom,
