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29 healthy adults and 32 male homosexuals were investigated for their humoral and cellular immunity against human cytomegalovirus (HCMV). In contrast to 30% of the controls, all homosexuals had HCMV serum antibodies. In addition, 84% of the homosexuals reacted positively in HCMV induced in vitro lymphocyte proliferation as compared to 66% of the controls. The study group also showed significantly higher mean reactivities in the lymphoproliferative response towards HCMV. In the group of homosexuals, a correlation could be established between the humoral and cellular immune reactivity to HCMV.
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