Bioaccumulation factor (BAF) plays a key role in identification of bioaccumulative substance and in assessment of chemical risks.In order to reveal the bioaccumulation behavior of fish in Dongjiang River,sediment,water and fish samples were collected from Dongjiang River and PBDEs,DBDPE,DP,TBBPA and HBCDs were measured.The ranges of lgBAF were 5.0-7.4,6.1-7.1,4.6-7.9,2.6-4.6 and 4.8-7.7,respectively.In the present study,most HFRs had a lgBAF of higher than 3.7,which suggested that they might be bioaccumulative.The BAF values of HFRs increased with increasing lgKow,when lgKow>7,the bioaccumulation extent decreased with the increase of lgKow.Biotransformation of γ-HBCD toward α-HBCD and the metabolism of BDE66 and BDE99 of these isomers might attribute to the deviation from the general trend predicted by Kow.More attention should be paid to DBDPE,since its BAF value was higher than that of BDE209.The BSAF values of most PBDEs,DBDPE,DP,TBBPA and HBCDs congeners in three fish species were less than 1,indicating that these compounds were unlikely to become a source of pollution to the aquatic organisms due to the poor bioavailability.