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T-lymphocyte subsets and human T-cell lymphotropic virus type III antibody prevalence were studied in African patients with the acquired immunodeficiency syndrome (AIDS) or AIDS-related complex (ARC), and in female prostitutes. African blood donors and healthy Zairian and Rwandese persons matched for age, sex, and annual income served as controls. Seropositivity was noted in 46 (87%) of 53 patients with AIDS, 29 (88%) of 33 patients with ARC, 67 (80%) of 84 prostitutes, and five (12.5%) of 40 and eight (15.5%) of 51 healthy controls and blood donors, respectively. Patients with AIDS and ARC had a significantly lower OKT4/OKT8 ratio than healthy African controls. These studies suggest that human T-cell lymphotropic virus type III infection has already spread extensively into the general African population and that female prostitutes could be an important human reservoir of AIDS virus in the heterosexual population.
N Clumeck, and
M Robert-Guroff, and
P Van de Perre, and
A Jennings, and
J Sibomana, and
P Demol, and
S Cran, and
R C Gallo
December 1985,
The Southeast Asian journal of tropical medicine and public health,
N Clumeck, and
M Robert-Guroff, and
P Van de Perre, and
A Jennings, and
J Sibomana, and
P Demol, and
S Cran, and
R C Gallo
January 1992,
Scandinavian journal of infectious diseases,
N Clumeck, and
M Robert-Guroff, and
P Van de Perre, and
A Jennings, and
J Sibomana, and
P Demol, and
S Cran, and
R C Gallo
October 1986,
The Western journal of medicine,
N Clumeck, and
M Robert-Guroff, and
P Van de Perre, and
A Jennings, and
J Sibomana, and
P Demol, and
S Cran, and
R C Gallo
May 1986,
American journal of public health,
N Clumeck, and
M Robert-Guroff, and
P Van de Perre, and
A Jennings, and
J Sibomana, and
P Demol, and
S Cran, and
R C Gallo
January 1986,
Medicina clinica,
N Clumeck, and
M Robert-Guroff, and
P Van de Perre, and
A Jennings, and
J Sibomana, and
P Demol, and
S Cran, and
R C Gallo
July 1990,
AIDS research and human retroviruses,
N Clumeck, and
M Robert-Guroff, and
P Van de Perre, and
A Jennings, and
J Sibomana, and
P Demol, and
S Cran, and
R C Gallo
July 1985,
Lancet (London, England),
N Clumeck, and
M Robert-Guroff, and
P Van de Perre, and
A Jennings, and
J Sibomana, and
P Demol, and
S Cran, and
R C Gallo
May 1987,
Medicina clinica,
N Clumeck, and
M Robert-Guroff, and
P Van de Perre, and
A Jennings, and
J Sibomana, and
P Demol, and
S Cran, and
R C Gallo
August 1985,
The New England journal of medicine,
N Clumeck, and
M Robert-Guroff, and
P Van de Perre, and
A Jennings, and
J Sibomana, and
P Demol, and
S Cran, and
R C Gallo
January 1986,
AIDS research,
