Influence of left ventricular function and other parameters on early and late mortality following coronary bypass surgery. 1977

B R Chaitman, and M G Bourassa, and A Heitz, and L Campeau

Left ventricular performance, coronary anatomy and postoperative clinical parameters of 66 control patients (group 1) randomly selected from 797 survivors of coronary bypass surgery were compared with those of 45 patients who died within 30 days of operation (group II) and 53 patients who died late (average, 22+/-2 mo) (group III). Average preoperative left ventricular end-diastolic pressure, ejection fraction and mean circumferential fibre shortening rate were significantly better in group I than in group III patients. These same parameters were not significantly different when group I was compared to group II. Abnormal wall motion was significantly less frequent in patients from group I than in patients from group II and III. Triple-vessel disease was present preoperatively in 40 (61%) controls compared with 37 (82%) early deaths (P = 0.021) and 35 (66%) late deaths (NS). The number of grafts placed per patient was not significantly different in the three groups. Perioperative myocardial in farction (MI) and low cardiac output syndrome were the commonest causes of early death. Late complications such as MI and heart failure occurred in 4 (6%) v; 15 (32%) (P = 0.0006) and 4 (6%) v. 27 (57%) (Pless than 0.0001) group I v. group III patients, respectively. Surgical expertise, preoperative ventricular performance and triple-vessel disease are important determinants of early mortality following bypass surgery and preoperative left ventricular performance is one of the most important determinants of late mortality,

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D003327 Coronary Disease An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels. Coronary Heart Disease,Coronary Diseases,Coronary Heart Diseases,Disease, Coronary,Disease, Coronary Heart,Diseases, Coronary,Diseases, Coronary Heart,Heart Disease, Coronary,Heart Diseases, Coronary
D005260 Female Females
D006321 Heart The hollow, muscular organ that maintains the circulation of the blood. Hearts
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001026 Coronary Artery Bypass Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion. Aortocoronary Bypass,Bypass, Coronary Artery,Bypass Surgery, Coronary Artery,Coronary Artery Bypass Grafting,Coronary Artery Bypass Surgery,Aortocoronary Bypasses,Artery Bypass, Coronary,Artery Bypasses, Coronary,Bypass, Aortocoronary,Bypasses, Aortocoronary,Bypasses, Coronary Artery,Coronary Artery Bypasses
D012189 Retrospective Studies Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons. Retrospective Study,Studies, Retrospective,Study, Retrospective

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