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In previous reports, children with acute lymphoblastic leukemia (ALL), who presented with T-cell markers on their lymphoblasts (T-lymphoblasts), have been predominantly older boys often with a mediastinal mass. These children are thought to constitute a subgroup of childhood ALL that has the poorest prognosis. Here, we report five girls with ALL, who presented with T-lymphoblasts but without a mediastinal mass. All responded well to chemotherapy and three of five are in maintained remission 21-33 months after diagnosis. The fourth patient died while in remission of causes other than leukemia and the fifth relapsed and died of infection two years after diagnosis. These observations suggest that girls with T-lymphoblasts may not have an adverse prognosis.
H W Hann, and
W T London, and
A E Evans
October 1973,
Journal of immunology (Baltimore, Md. : 1950),
H W Hann, and
W T London, and
A E Evans
April 1975,
The New England journal of medicine,
H W Hann, and
W T London, and
A E Evans
September 1974,
Cancer,
H W Hann, and
W T London, and
A E Evans
January 1986,
Pediatric hematology and oncology,
H W Hann, and
W T London, and
A E Evans
January 1974,
Zeitschrift fur Kinderheilkunde,
H W Hann, and
W T London, and
A E Evans
November 1979,
[Rinsho ketsueki] The Japanese journal of clinical hematology,
H W Hann, and
W T London, and
A E Evans
November 1980,
International journal of cancer,
H W Hann, and
W T London, and
A E Evans
January 1985,
Clinical and laboratory haematology,
H W Hann, and
W T London, and
A E Evans
November 1980,
Blut,
H W Hann, and
W T London, and
A E Evans
January 1980,
Blood,
