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"Stunned" myocardium prevents the assessment of myocardial salvage after streptokinase. In order to unmask "stunning," we sought to evaluate left ventricular inotropic contractile reserve of patients after streptokinase. Radionuclide ventriculograms were obtained in 75 consecutive patients 2 weeks after myocardial infarction, at rest and during intravenous isoproterenol infusion. Resting and isoproterenol-stressed ejection fractions were compared in the patent and closed-infarct vessel groups. Although there was no difference in the resting ejection fractions between the patent group (0.48 +/- 0.02) and the closed group (0.48 +/- 0.02), isoproterenol increased the ejection fractions in the patent group (increase 0.14 +/- 0.01) significantly more than in the closed group (increase 0.06 +/- 0.01) (p less than 0.0001). Thus, despite identical resting ventricular function, the greater inotropic contractile reserve in the patent infarct vessel group suggests that restoration of blood flow in acute myocardial infarction salvages myocardium.
L F Satler, and
K M Kent, and
L M Fox, and
H A Goldstein, and
C E Green, and
W J Rogers, and
R S Pallas, and
A A Del Negro, and
D L Pearle, and
C E Rackley
November 1994,
The American journal of cardiology,
L F Satler, and
K M Kent, and
L M Fox, and
H A Goldstein, and
C E Green, and
W J Rogers, and
R S Pallas, and
A A Del Negro, and
D L Pearle, and
C E Rackley
August 1992,
American heart journal,
L F Satler, and
K M Kent, and
L M Fox, and
H A Goldstein, and
C E Green, and
W J Rogers, and
R S Pallas, and
A A Del Negro, and
D L Pearle, and
C E Rackley
September 1989,
Lancet (London, England),
L F Satler, and
K M Kent, and
L M Fox, and
H A Goldstein, and
C E Green, and
W J Rogers, and
R S Pallas, and
A A Del Negro, and
D L Pearle, and
C E Rackley
September 2008,
Journal of cardiovascular medicine (Hagerstown, Md.),
L F Satler, and
K M Kent, and
L M Fox, and
H A Goldstein, and
C E Green, and
W J Rogers, and
R S Pallas, and
A A Del Negro, and
D L Pearle, and
C E Rackley
May 1993,
Oral surgery, oral medicine, and oral pathology,
L F Satler, and
K M Kent, and
L M Fox, and
H A Goldstein, and
C E Green, and
W J Rogers, and
R S Pallas, and
A A Del Negro, and
D L Pearle, and
C E Rackley
October 1992,
Postgraduate medical journal,
L F Satler, and
K M Kent, and
L M Fox, and
H A Goldstein, and
C E Green, and
W J Rogers, and
R S Pallas, and
A A Del Negro, and
D L Pearle, and
C E Rackley
May 1991,
Annals of internal medicine,
L F Satler, and
K M Kent, and
L M Fox, and
H A Goldstein, and
C E Green, and
W J Rogers, and
R S Pallas, and
A A Del Negro, and
D L Pearle, and
C E Rackley
August 2001,
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions,
L F Satler, and
K M Kent, and
L M Fox, and
H A Goldstein, and
C E Green, and
W J Rogers, and
R S Pallas, and
A A Del Negro, and
D L Pearle, and
C E Rackley
October 2003,
Saudi medical journal,
L F Satler, and
K M Kent, and
L M Fox, and
H A Goldstein, and
C E Green, and
W J Rogers, and
R S Pallas, and
A A Del Negro, and
D L Pearle, and
C E Rackley
April 1989,
Journal of the Tennessee Medical Association,
