-transparent.png){kind=logo}
Twenty-three patients with inoperable non-small cell lung cancer were treated with a combination chemotherapy of CDDP 100 mg/m2, ADM 30 mg/m2 and MMC 8 mg/m2 (PAM). Ten cases were adenocarcinoma, 9 cases were squamous cell carcinoma and 4 cases were large cell carcinoma. In 21 evaluable cases, partial response was obtained in 47.6%. (The response rates were 40.0% in patients with adenocarcinoma, 50.0% in those with squamous cell carcinoma and 66.7% in those with large cell carcinoma.) Leukocytopenia of less than 4,000/mm3 occurred in 100% of cases, thrombocytopenia of less than 100,000/mm3 occurred in 81.0%, and anemia(fall in hemoglobin over 2.0 g/dl) occurred in 66.7%. A transient elevation of Cr (over 1.5 mg/dl) and/or BUN (over 30 mg/dl) was observed in 23.8%. Nausea and vomiting occurred in almost all patients. No death occurred due to toxicity of PAM. These results demonstrate that PAM is an effective combination chemotherapy in patients with non-small cell carcinoma of the lung.
H Nakano, and
M Kurihara, and
R Saito, and
A Takise, and
S Tsuchiya, and
K Minato, and
K Takehara, and
T Saruya, and
H Kuwabara, and
R Fueki
December 1990,
Journal of chemotherapy (Florence, Italy),
H Nakano, and
M Kurihara, and
R Saito, and
A Takise, and
S Tsuchiya, and
K Minato, and
K Takehara, and
T Saruya, and
H Kuwabara, and
R Fueki
February 1984,
Gan to kagaku ryoho. Cancer & chemotherapy,
H Nakano, and
M Kurihara, and
R Saito, and
A Takise, and
S Tsuchiya, and
K Minato, and
K Takehara, and
T Saruya, and
H Kuwabara, and
R Fueki
December 1987,
Gan to kagaku ryoho. Cancer & chemotherapy,
H Nakano, and
M Kurihara, and
R Saito, and
A Takise, and
S Tsuchiya, and
K Minato, and
K Takehara, and
T Saruya, and
H Kuwabara, and
R Fueki
February 1993,
Gan to kagaku ryoho. Cancer & chemotherapy,
H Nakano, and
M Kurihara, and
R Saito, and
A Takise, and
S Tsuchiya, and
K Minato, and
K Takehara, and
T Saruya, and
H Kuwabara, and
R Fueki
October 1981,
Cancer,
H Nakano, and
M Kurihara, and
R Saito, and
A Takise, and
S Tsuchiya, and
K Minato, and
K Takehara, and
T Saruya, and
H Kuwabara, and
R Fueki
December 1984,
Gan to kagaku ryoho. Cancer & chemotherapy,
H Nakano, and
M Kurihara, and
R Saito, and
A Takise, and
S Tsuchiya, and
K Minato, and
K Takehara, and
T Saruya, and
H Kuwabara, and
R Fueki
January 1985,
Medical and pediatric oncology,
H Nakano, and
M Kurihara, and
R Saito, and
A Takise, and
S Tsuchiya, and
K Minato, and
K Takehara, and
T Saruya, and
H Kuwabara, and
R Fueki
September 1985,
Gan no rinsho. Japan journal of cancer clinics,
H Nakano, and
M Kurihara, and
R Saito, and
A Takise, and
S Tsuchiya, and
K Minato, and
K Takehara, and
T Saruya, and
H Kuwabara, and
R Fueki
January 1991,
Cancer chemotherapy and pharmacology,
H Nakano, and
M Kurihara, and
R Saito, and
A Takise, and
S Tsuchiya, and
K Minato, and
K Takehara, and
T Saruya, and
H Kuwabara, and
R Fueki
January 1979,
Cancer treatment reports,
