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Serum samples from 313 asymptomatic intravenous (IV) drug users from Bilbao (Vizcaya, Vasque Country, Spain) were tested for antibodies to HTLV-III/LAV virus, the probable etiologic agent of the acquired immune deficiency syndrome (AIDS). Viral antibodies were assayed by ELISA test. 41.9% of the sera gave positive reactions. No seropositivity was detected among 22 normal blood donors, 58 chronic alcoholics, or 20 members of the Drug Control Center personnel. Virus specific reactions were confirmed by indirect immunofluorescence using an HTLV-III/LAV producer cell line, and by Western blotting. 55% of the ELISA-positive sera were also positive in Western blot assay. No differences in seropositivity by age or sex were observed but it increased with the period of parenteral drug use. Presence of antibody statistically correlated with the frequency of syringe sharing, confirming the transmission of viral infection by blood products. Altered T4/T8 ratios and lower number of T4 positive lymphocytes were detected among HTLV-III/LAV positive drug addicts.
F Merino, and
B Esparza, and
J Aizpiri, and
J Fernandez, and
L de Masdelval, and
A Arrieta, and
M Velazquez, and
D J Volsky, and
E San Cristobal, and
A de Izaguirre
August 1985,
Schweizerische medizinische Wochenschrift,
F Merino, and
B Esparza, and
J Aizpiri, and
J Fernandez, and
L de Masdelval, and
A Arrieta, and
M Velazquez, and
D J Volsky, and
E San Cristobal, and
A de Izaguirre
July 1985,
Lancet (London, England),
F Merino, and
B Esparza, and
J Aizpiri, and
J Fernandez, and
L de Masdelval, and
A Arrieta, and
M Velazquez, and
D J Volsky, and
E San Cristobal, and
A de Izaguirre
January 1987,
Microbiologica,
F Merino, and
B Esparza, and
J Aizpiri, and
J Fernandez, and
L de Masdelval, and
A Arrieta, and
M Velazquez, and
D J Volsky, and
E San Cristobal, and
A de Izaguirre
August 1986,
Journal of medical virology,
F Merino, and
B Esparza, and
J Aizpiri, and
J Fernandez, and
L de Masdelval, and
A Arrieta, and
M Velazquez, and
D J Volsky, and
E San Cristobal, and
A de Izaguirre
September 1986,
Revista clinica espanola,
F Merino, and
B Esparza, and
J Aizpiri, and
J Fernandez, and
L de Masdelval, and
A Arrieta, and
M Velazquez, and
D J Volsky, and
E San Cristobal, and
A de Izaguirre
April 1986,
Deutsche medizinische Wochenschrift (1946),
F Merino, and
B Esparza, and
J Aizpiri, and
J Fernandez, and
L de Masdelval, and
A Arrieta, and
M Velazquez, and
D J Volsky, and
E San Cristobal, and
A de Izaguirre
November 1985,
Lakartidningen,
F Merino, and
B Esparza, and
J Aizpiri, and
J Fernandez, and
L de Masdelval, and
A Arrieta, and
M Velazquez, and
D J Volsky, and
E San Cristobal, and
A de Izaguirre
January 1986,
Medicina clinica,
F Merino, and
B Esparza, and
J Aizpiri, and
J Fernandez, and
L de Masdelval, and
A Arrieta, and
M Velazquez, and
D J Volsky, and
E San Cristobal, and
A de Izaguirre
July 1986,
Quintessenz Journal,
F Merino, and
B Esparza, and
J Aizpiri, and
J Fernandez, and
L de Masdelval, and
A Arrieta, and
M Velazquez, and
D J Volsky, and
E San Cristobal, and
A de Izaguirre
January 1986,
Pennsylvania medicine,
