-transparent.png){kind=logo}
Since many malignancies often occur in patients with smoldering type adult T-cell leukemia (ATL) (5 of 18 cases in this report), the relationship between HTLV-I (human T-cell leukemia virus type I) infection, which is closely associated with ATL, with other malignancies in an HTLV-I endemic area was examined. Among the 394 patients with malignancies and who had not had blood cell transfusions, 61 (15.5%) tested positive for HTLV-I antibody. The prevalence was significantly higher in males older than age 40 years and females of all ages compared to age- and sex-matched healthy individuals. The overall seroprevalence (26.1%) in 291 patients with malignancies and who had had blood cell transfusions was higher than that of those who had not had blood transfusions. There was no significant correlation between the site of malignancy and antibody prevalence. These results suggest the possibility that development of malignancy may contribute to expression of latent HTLV-I infection and that HTLV-I infection may contribute to the risk of other malignancies.
N Asou, and
T Kumagai, and
S Uekihara, and
M Ishii, and
M Sato, and
K Sakai, and
H Nishimura, and
K Yamaguchi, and
K Takatsuki
June 1992,
The New England journal of medicine,
N Asou, and
T Kumagai, and
S Uekihara, and
M Ishii, and
M Sato, and
K Sakai, and
H Nishimura, and
K Yamaguchi, and
K Takatsuki
June 1992,
The New England journal of medicine,
N Asou, and
T Kumagai, and
S Uekihara, and
M Ishii, and
M Sato, and
K Sakai, and
H Nishimura, and
K Yamaguchi, and
K Takatsuki
January 1994,
Japanese journal of ophthalmology,
N Asou, and
T Kumagai, and
S Uekihara, and
M Ishii, and
M Sato, and
K Sakai, and
H Nishimura, and
K Yamaguchi, and
K Takatsuki
February 1991,
The British journal of ophthalmology,
N Asou, and
T Kumagai, and
S Uekihara, and
M Ishii, and
M Sato, and
K Sakai, and
H Nishimura, and
K Yamaguchi, and
K Takatsuki
January 1996,
Revista da Sociedade Brasileira de Medicina Tropical,
N Asou, and
T Kumagai, and
S Uekihara, and
M Ishii, and
M Sato, and
K Sakai, and
H Nishimura, and
K Yamaguchi, and
K Takatsuki
May 1991,
Revista medica de Chile,
N Asou, and
T Kumagai, and
S Uekihara, and
M Ishii, and
M Sato, and
K Sakai, and
H Nishimura, and
K Yamaguchi, and
K Takatsuki
June 1994,
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
N Asou, and
T Kumagai, and
S Uekihara, and
M Ishii, and
M Sato, and
K Sakai, and
H Nishimura, and
K Yamaguchi, and
K Takatsuki
October 1992,
Journal of acquired immune deficiency syndromes,
N Asou, and
T Kumagai, and
S Uekihara, and
M Ishii, and
M Sato, and
K Sakai, and
H Nishimura, and
K Yamaguchi, and
K Takatsuki
September 1994,
Bone marrow transplantation,
N Asou, and
T Kumagai, and
S Uekihara, and
M Ishii, and
M Sato, and
K Sakai, and
H Nishimura, and
K Yamaguchi, and
K Takatsuki
July 1993,
International journal of cancer,
