The importance of right ventricular function in patients with pulmonary arterial hypertension. 2018

Roberto Badagliacca, and Silvia Papa, and Roberto Poscia, and Beatrice Pezzuto, and Giovanna Manzi, and Roberto Torre, and Francesco Fedele, and Carmine Dario Vizza
a Department of Cardiovascular and Respiratory Science , Sapienza University of Rome , Rome , Italy.

Pulmonary arterial hypertension (PAH) is a progressive, life-threatening, and incurable disease. Its prognosis is based on right ventricular (RV) function. Therefore, adequate assessment of RV function is mandatory. Areas covered: This article presents the case of a patient with PAH in which the traditional diagnostic approach did not provide a complete assessment of RV function. The authors show how the analysis of other parameters yielded additional information that improved the management of this patient. Expert commentary: Despite current treatments, PAH often worsens due to progressive RV dysfunction. Appropriate assessment of RV function may facilitate the early identification of patients at risk of RV function impairment. More aggressive treatment of PAH might delay progression of the disease. Traditional risk stratification, which is based on New York Heart Association/World Health Organization (NYHA/WHO) functional class evaluation, the 6-minute walk test, and right heart catheterization, proves insufficient in many PAH patients, as it does not provide complete information about RV function. Thus, further parameters are required. Analysis of RV function, in addition to echocardiography and cardiopulmonary exercise testing, may add relevant prognostic information and improve therapy.

UI MeSH Term Description Entries
D006976 Hypertension, Pulmonary Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES. Pulmonary Hypertension
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011379 Prognosis A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations. Prognostic Factor,Prognostic Factors,Factor, Prognostic,Factors, Prognostic,Prognoses
D004452 Echocardiography Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic. Echocardiography, Contrast,Echocardiography, Cross-Sectional,Echocardiography, M-Mode,Echocardiography, Transthoracic,Echocardiography, Two-Dimensional,Transthoracic Echocardiography,2-D Echocardiography,2D Echocardiography,Contrast Echocardiography,Cross-Sectional Echocardiography,Echocardiography, 2-D,Echocardiography, 2D,M-Mode Echocardiography,Two-Dimensional Echocardiography,2 D Echocardiography,Cross Sectional Echocardiography,Echocardiography, 2 D,Echocardiography, Cross Sectional,Echocardiography, M Mode,Echocardiography, Two Dimensional,M Mode Echocardiography,Two Dimensional Echocardiography
D005080 Exercise Test Controlled physical activity which is performed in order to allow assessment of physiological functions, particularly cardiovascular and pulmonary, but also aerobic capacity. Maximal (most intense) exercise is usually required but submaximal exercise is also used. Arm Ergometry Test,Bicycle Ergometry Test,Cardiopulmonary Exercise Testing,Exercise Testing,Step Test,Stress Test,Treadmill Test,Cardiopulmonary Exercise Test,EuroFit Tests,Eurofit Test Battery,European Fitness Testing Battery,Fitness Testing,Physical Fitness Testing,Arm Ergometry Tests,Bicycle Ergometry Tests,Cardiopulmonary Exercise Tests,Ergometry Test, Arm,Ergometry Test, Bicycle,Ergometry Tests, Arm,Ergometry Tests, Bicycle,EuroFit Test,Eurofit Test Batteries,Exercise Test, Cardiopulmonary,Exercise Testing, Cardiopulmonary,Exercise Tests,Exercise Tests, Cardiopulmonary,Fitness Testing, Physical,Fitness Testings,Step Tests,Stress Tests,Test Battery, Eurofit,Test, Arm Ergometry,Test, Bicycle Ergometry,Test, Cardiopulmonary Exercise,Test, EuroFit,Test, Exercise,Test, Step,Test, Stress,Test, Treadmill,Testing, Cardiopulmonary Exercise,Testing, Exercise,Testing, Fitness,Testing, Physical Fitness,Tests, Arm Ergometry,Tests, Bicycle Ergometry,Tests, Cardiopulmonary Exercise,Tests, EuroFit,Tests, Exercise,Tests, Step,Tests, Stress,Tests, Treadmill,Treadmill Tests
D006328 Cardiac Catheterization Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures. Catheterization, Cardiac,Catheterization, Heart,Heart Catheterization,Cardiac Catheterizations,Catheterizations, Cardiac,Catheterizations, Heart,Heart Catheterizations
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000072226 Computed Tomography Angiography A non-invasive method that uses a CT scanner for capturing images of blood vessels and tissues. A CONTRAST MATERIAL is injected, which helps produce detailed images that aid in diagnosing VASCULAR DISEASES. Angiography, CT,Angiography, Computed Tomography,CT Angiography,Angiographies, CT,Angiographies, Computed Tomography,CT Angiographies,Computed Tomography Angiographies,Tomography Angiographies, Computed,Tomography Angiography, Computed
D016278 Ventricular Function, Right The hemodynamic and electrophysiological action of the right HEART VENTRICLE. Right Ventricular Function,Function, Right Ventricular,Functions, Right Ventricular,Right Ventricular Functions,Ventricular Functions, Right

Related Publications

Roberto Badagliacca, and Silvia Papa, and Roberto Poscia, and Beatrice Pezzuto, and Giovanna Manzi, and Roberto Torre, and Francesco Fedele, and Carmine Dario Vizza
September 2019, Herz,
Roberto Badagliacca, and Silvia Papa, and Roberto Poscia, and Beatrice Pezzuto, and Giovanna Manzi, and Roberto Torre, and Francesco Fedele, and Carmine Dario Vizza
August 2022, Heart (British Cardiac Society),
Roberto Badagliacca, and Silvia Papa, and Roberto Poscia, and Beatrice Pezzuto, and Giovanna Manzi, and Roberto Torre, and Francesco Fedele, and Carmine Dario Vizza
September 2022, Medicine,
Roberto Badagliacca, and Silvia Papa, and Roberto Poscia, and Beatrice Pezzuto, and Giovanna Manzi, and Roberto Torre, and Francesco Fedele, and Carmine Dario Vizza
July 2021, Clinical rheumatology,
Roberto Badagliacca, and Silvia Papa, and Roberto Poscia, and Beatrice Pezzuto, and Giovanna Manzi, and Roberto Torre, and Francesco Fedele, and Carmine Dario Vizza
January 2011, Radiology,
Roberto Badagliacca, and Silvia Papa, and Roberto Poscia, and Beatrice Pezzuto, and Giovanna Manzi, and Roberto Torre, and Francesco Fedele, and Carmine Dario Vizza
October 2021, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation,
Roberto Badagliacca, and Silvia Papa, and Roberto Poscia, and Beatrice Pezzuto, and Giovanna Manzi, and Roberto Torre, and Francesco Fedele, and Carmine Dario Vizza
December 2018, Heart, lung & circulation,
Roberto Badagliacca, and Silvia Papa, and Roberto Poscia, and Beatrice Pezzuto, and Giovanna Manzi, and Roberto Torre, and Francesco Fedele, and Carmine Dario Vizza
October 2013, Circulation,
Roberto Badagliacca, and Silvia Papa, and Roberto Poscia, and Beatrice Pezzuto, and Giovanna Manzi, and Roberto Torre, and Francesco Fedele, and Carmine Dario Vizza
January 1991, Polski tygodnik lekarski (Warsaw, Poland : 1960),
Roberto Badagliacca, and Silvia Papa, and Roberto Poscia, and Beatrice Pezzuto, and Giovanna Manzi, and Roberto Torre, and Francesco Fedele, and Carmine Dario Vizza
January 2013, The Journal of rheumatology,
Copied contents to your clipboard!