Polyglycolic acid mesh in repair of renal injury. 1986

A M Mounzer, and J W McAninch, and R A Schmidt

To evaluate the use of a polyglycolic acid (PGA) mesh graft for partial nephrectomy, we replaced the upper pole of the left kidney in 12 New Zealand white rabbits with a free omental fat graft and the lower pole with PGA mesh. The mesh stopped the bleeding immediately during the operation. At forty-eight hours, the fibers were still intact, with an organized clot on the surface of the mesh. Between two weeks and two months, the fibers had begun to be digested by histiocytes, with formation of giant cells and fibroblastic proliferation with collagen deposition around the mesh. At three months, there was complete resorption of the PGA mesh and formation of a new fibrous capsule. There was no renal reaction and no difference between the PGA mesh and the omental fat graft. We believe that PGA mesh can be helpful in repairing injured kidneys by securing hemostasis and serving as a scaffold for the formation of a new capsule.

UI MeSH Term Description Entries
D007668 Kidney Body organ that filters blood for the secretion of URINE and that regulates ion concentrations. Kidneys
D009392 Nephrectomy Excision of kidney. Heminephrectomy,Heminephrectomies,Nephrectomies
D009852 Omentum A double-layered fold of peritoneum that attaches the STOMACH to other organs in the ABDOMINAL CAVITY. Omentums
D011100 Polyglycolic Acid A biocompatible polymer used as a surgical suture material. Polyglycolide,Biofix,Dexon (Polyester),Dexon-S,Dexon S,DexonS
D011817 Rabbits A burrowing plant-eating mammal with hind limbs that are longer than its fore limbs. It belongs to the family Leporidae of the order Lagomorpha, and in contrast to hares, possesses 22 instead of 24 pairs of chromosomes. Belgian Hare,New Zealand Rabbit,New Zealand Rabbits,New Zealand White Rabbit,Rabbit,Rabbit, Domestic,Chinchilla Rabbits,NZW Rabbits,New Zealand White Rabbits,Oryctolagus cuniculus,Chinchilla Rabbit,Domestic Rabbit,Domestic Rabbits,Hare, Belgian,NZW Rabbit,Rabbit, Chinchilla,Rabbit, NZW,Rabbit, New Zealand,Rabbits, Chinchilla,Rabbits, Domestic,Rabbits, NZW,Rabbits, New Zealand,Zealand Rabbit, New,Zealand Rabbits, New,cuniculus, Oryctolagus
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D013526 Surgical Mesh Any woven or knit material of open texture used in surgery for the repair, reconstruction, or substitution of tissue. The mesh is usually a synthetic fabric made of various polymers. It is occasionally made of metal. Mesh, Surgical,Meshes, Surgical,Surgical Meshes

Related Publications

A M Mounzer, and J W McAninch, and R A Schmidt
September 1986, The Journal of urology,
A M Mounzer, and J W McAninch, and R A Schmidt
December 2007, Diseases of the colon and rectum,
A M Mounzer, and J W McAninch, and R A Schmidt
January 1987, Current surgery,
A M Mounzer, and J W McAninch, and R A Schmidt
January 1997, European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes,
A M Mounzer, and J W McAninch, and R A Schmidt
January 2012, JSLS : Journal of the Society of Laparoendoscopic Surgeons,
A M Mounzer, and J W McAninch, and R A Schmidt
June 1987, The Journal of trauma,
A M Mounzer, and J W McAninch, and R A Schmidt
January 1990, Annales chirurgiae et gynaecologiae,
A M Mounzer, and J W McAninch, and R A Schmidt
March 1986, The Journal of trauma,
A M Mounzer, and J W McAninch, and R A Schmidt
September 1995, Annals of plastic surgery,
A M Mounzer, and J W McAninch, and R A Schmidt
October 2015, Asian cardiovascular & thoracic annals,
Copied contents to your clipboard!