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The damaging effect of high-energy helium ions (4 GeV), protons (9 GeV), and standard radiation was different as studied on Chinese hamster cell cultures (clone 431). A possibility of increasing the survival of cells by the pre- and post-irradiation treatment with a mesoporphyrin-IX derivative was demonstrated. It is suggested that the radioprotective effect of the modifier is associated with the decreased level of aberrant mitoses.
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