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The mechanisms underlying delayed-type hypersensitivity (DTH) response in mouse hepatitis virus (MHV) infection was studied using high responder B10.D2 and low responder DBA/2 mice. Bone-marrow chimeras expressed the DTH responses at the same degree as the donors. The involvement of suppressor cells in low DTH response in DBA/2 mice seems unlikely since transfer of DBA/2 spleen cells to B10.D2 mice did not suppress the response. Transfer of B10.D2 spleen cells to DBA/2 mice caused no changes in DTH response of the recipients. MHV-infected mice, which were irradiated with 500 rad of gamma-ray and then given B10.D2 bone-marrow cells 8 days p.i., showed higher DTH responses than those given DBA/2 bone-marrow cells. These results suggest that the difference in DTH responsiveness to MHV between the two mouse strains is dependent on the activity of bone-marrow cells.
S Kyuwa, and
K Yamaguchi, and
K Fujiwara, and
K Yamanouchi
April 1984,
The Japanese journal of experimental medicine,
S Kyuwa, and
K Yamaguchi, and
K Fujiwara, and
K Yamanouchi
October 1984,
The Japanese journal of experimental medicine,
S Kyuwa, and
K Yamaguchi, and
K Fujiwara, and
K Yamanouchi
September 1981,
Scandinavian journal of immunology,
S Kyuwa, and
K Yamaguchi, and
K Fujiwara, and
K Yamanouchi
February 1994,
The Journal of veterinary medical science,
S Kyuwa, and
K Yamaguchi, and
K Fujiwara, and
K Yamanouchi
April 1981,
Journal of immunology (Baltimore, Md. : 1950),
S Kyuwa, and
K Yamaguchi, and
K Fujiwara, and
K Yamanouchi
January 1978,
Microbiology and immunology,
S Kyuwa, and
K Yamaguchi, and
K Fujiwara, and
K Yamanouchi
January 1982,
Medical microbiology and immunology,
S Kyuwa, and
K Yamaguchi, and
K Fujiwara, and
K Yamanouchi
November 1986,
Arerugi = [Allergy],
S Kyuwa, and
K Yamaguchi, and
K Fujiwara, and
K Yamanouchi
December 1987,
Laboratory animal science,
S Kyuwa, and
K Yamaguchi, and
K Fujiwara, and
K Yamanouchi
January 1980,
Scandinavian journal of immunology,
