Biomechanical Evaluation of Osteoporotic Proximal Periprosthetic Femur Fractures With Proximal Bicortical Fixation and Allograft Struts. 2018

Robert S OʼConnell, and John R Owen, and Erik J Hansen, and Azhar S Bashir, and Jennifer S Wayne, and Jibanananda Satpathy, and Stephen L Kates
Department of Orthopaedic Surgery, VCU Health System, Richmond, VA.

To evaluate the strength of proximal bicortical fixation using a novel osteoporotic synthetic bone model of Vancouver B1 periprosthetic proximal periprosthetic femur fractures (PFFs) and to assess the influence of strut allograft augmentation with regard to allowing early assisted weight bearing. The secondary aim was to evaluate whether the strut position, either medial or anterior, influenced the strength of the construct. Thirty synthetic osteoporotic femurs were implanted with cemented stems. A segmental defect made distal to the stem simulated a fracture and was repaired with a stainless steel locking compression plate and 2 stainless steel proximal locking attachment plates. Specimens were then divided into 3 groups: no-strut, medial strut, and anterior strut. Cadaveric femoral struts were wired to the specimens. Cyclic axial compression simulated assisted weight bearing and was followed by loading to failure. Medial struts required higher failure load than no-strut (P = 0.008) and more energy to failure than anterior (P = 0.018) or no-strut (P < 0.001). The higher load to failure, however, would not be advantageous in clinical practice because estimates for assisted weight bearing after fractures in average-weight patients are well below these failure loads. Furthermore, all specimens tolerated cyclical loading. All failures occurred distal to the plate originating at the last screw hole. Failure loads for all groups were above what would be expected for low-demand activities of assisted weight bearing. Therefore, proximal bicortical fixation should allow for early, assisted weight bearing without allograft strut augmentation even with lower density bone.

UI MeSH Term Description Entries
D008422 Materials Testing The testing of materials and devices, especially those used for PROSTHESES AND IMPLANTS; SUTURES; TISSUE ADHESIVES; etc., for hardness, strength, durability, safety, efficacy, and biocompatibility. Biocompatibility Testing,Biocompatible Materials Testing,Hemocompatibility Testing,Testing, Biocompatible Materials,Testing, Hemocompatible Materials,Hemocompatibility Testings,Hemocompatible Materials Testing,Materials Testing, Biocompatible,Materials Testing, Hemocompatible,Testing, Biocompatibility,Testing, Hemocompatibility,Testing, Materials,Testings, Biocompatibility
D010024 Osteoporosis Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis. Age-Related Osteoporosis,Bone Loss, Age-Related,Osteoporosis, Age-Related,Osteoporosis, Post-Traumatic,Osteoporosis, Senile,Senile Osteoporosis,Osteoporosis, Involutional,Age Related Osteoporosis,Age-Related Bone Loss,Age-Related Bone Losses,Age-Related Osteoporoses,Bone Loss, Age Related,Bone Losses, Age-Related,Osteoporoses,Osteoporoses, Age-Related,Osteoporoses, Senile,Osteoporosis, Age Related,Osteoporosis, Post Traumatic,Post-Traumatic Osteoporoses,Post-Traumatic Osteoporosis,Senile Osteoporoses
D001864 Bone Wires Steel wires, often threaded through the skin, soft tissues, and bone, used to fix broken bones. Kirschner wires or apparatus also includes the application of traction to the healing bones through the wires. Kirschner Wire,Kirschner Wires,Bone Wire,Wire, Bone,Wire, Kirschner,Wires, Bone,Wires, Kirschner
D005264 Femoral Fractures Fractures of the femur. Femoral Fracture,Fracture, Femoral,Fractures, Femoral
D005593 Fracture Fixation, Internal The use of internal devices (metal plates, nails, rods, etc.) to hold the position of a fracture in proper alignment. Osteosynthesis, Fracture,Fixation, Internal Fracture,Fixations, Internal Fracture,Fracture Fixations, Internal,Fracture Osteosyntheses,Fracture Osteosynthesis,Internal Fracture Fixation,Internal Fracture Fixations,Osteosyntheses, Fracture
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001696 Biomechanical Phenomena The properties, processes, and behavior of biological systems under the action of mechanical forces. Biomechanics,Kinematics,Biomechanic Phenomena,Mechanobiological Phenomena,Biomechanic,Biomechanic Phenomenas,Phenomena, Biomechanic,Phenomena, Biomechanical,Phenomena, Mechanobiological,Phenomenas, Biomechanic
D012680 Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed) Specificity,Sensitivity,Specificity and Sensitivity
D013314 Stress, Mechanical A purely physical condition which exists within any material because of strain or deformation by external forces or by non-uniform thermal expansion; expressed quantitatively in units of force per unit area. Mechanical Stress,Mechanical Stresses,Stresses, Mechanical
D016474 Weight-Bearing The physical state of supporting an applied load. This often refers to the weight-bearing bones or joints that support the body's weight, especially those in the spine, hip, knee, and foot. Load-Bearing,Axial Loading,Loadbearing,Weightbearing,Axial Loadings,Load Bearing,Weight Bearing

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