-transparent.png){kind=logo}
A complementary DNA clone encoding human pre-pro gastrin-releasing peptide, a 27-amino acid neuropeptide and putative growth factor, was used to determine the chromosomal location of this gene. Southern blot hybridization to genomic DNA isolated from a panel of human-rodent somatic cell hybrids unambiguously maps this gene to human chromosome 18. In situ chromosomal hybridization confirms the hybrid data and further localized the gene to chromosome band 18q21. Karyotypic abnormalities in tumors and inherited disease states which involve chromosome band 18q21 may now be studied for correlated changes in the structure and expression of the human GRP gene.
Related Publications
A M Lebacq-Verheyden, and
V Bertness, and
I Kirsch, and
G F Hollis, and
O W McBride, and
J Battey
January 1987,
Somatic cell and molecular genetics,
A M Lebacq-Verheyden, and
V Bertness, and
I Kirsch, and
G F Hollis, and
O W McBride, and
J Battey
January 1995,
Cytogenetics and cell genetics,
A M Lebacq-Verheyden, and
V Bertness, and
I Kirsch, and
G F Hollis, and
O W McBride, and
J Battey
January 2000,
American journal of medical genetics,
A M Lebacq-Verheyden, and
V Bertness, and
I Kirsch, and
G F Hollis, and
O W McBride, and
J Battey
October 2014,
Psychiatric genetics,
A M Lebacq-Verheyden, and
V Bertness, and
I Kirsch, and
G F Hollis, and
O W McBride, and
J Battey
March 1994,
Genomics,
A M Lebacq-Verheyden, and
V Bertness, and
I Kirsch, and
G F Hollis, and
O W McBride, and
J Battey
October 2000,
Molecules and cells,
A M Lebacq-Verheyden, and
V Bertness, and
I Kirsch, and
G F Hollis, and
O W McBride, and
J Battey
January 1995,
Cytogenetics and cell genetics,
A M Lebacq-Verheyden, and
V Bertness, and
I Kirsch, and
G F Hollis, and
O W McBride, and
J Battey
May 1996,
Genomics,
A M Lebacq-Verheyden, and
V Bertness, and
I Kirsch, and
G F Hollis, and
O W McBride, and
J Battey
July 1995,
Genomics,
A M Lebacq-Verheyden, and
V Bertness, and
I Kirsch, and
G F Hollis, and
O W McBride, and
J Battey
October 1993,
Oncogene,
