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Three Cases of Idiopathic Diffuse Pulmonary Ossification. 2019
Ryuya Edahiro, and
Hiroyuki Kurebe, and
Saeko Nakatsubo, and
Yuki Hosono, and
Nobuhiko Sawa, and
Kohei Nishida, and
Yuko Ohara, and
Yohei Oshitani, and
Hiroyuki Kagawa, and
Kazuyuki Tsujino, and
Kenji Yoshimura, and
Keisuke Miki, and
Mari Miki, and
Seigo Kitada, and
Masahide Mori
Department of Respiratory Medicine, National Hospital Organization Toneyama National Hospital, Japan.
Diffuse pulmonary ossification (DPO) is an uncommon diffuse lung disease characterized by metaplastic bone formation in the lung parenchyma and is rarely diagnosed in life. While DPO usually occurs as a secondary disease, idiopathic cases are extremely rare. We describe three cases of idiopathic DPO, two of which were definitively diagnosed by surgical lung biopsy. One case was observed in a 43-year-old man with a history of recurrent pneumothorax who developed pneumothorax after the surgical biopsy. Few reports have described cases of DPO with recurrent pneumothorax; however, pneumothorax should be considered as a potential complication when such patients are encountered.
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