RIFM fragrance ingredient safety assessment, 3a,4,5,6,7,7a-hexahydromethoxy-4,7-methano-1H-indene (isomer unspecified), CAS Registry Number 27135-90-6. 2018

A M Api, and D Belsito, and D Botelho, and M Bruze, and G A Burton, and J Buschmann, and M L Dagli, and M Date, and W Dekant, and C Deodhar, and M Francis, and A D Fryer, and L Jones, and K Joshi, and S La Cava, and A Lapczynski, and D C Liebler, and D O'Brien, and A Patel, and T M Penning, and G Ritacco, and J Romine, and N Sadekar, and D Salvito, and T W Schultz, and I G Sipes, and G Sullivan, and Y Thakkar, and Y Tokura, and S Tsang
Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.

UI MeSH Term Description Entries
D007192 Indenes A family of fused-ring hydrocarbons isolated from coal tar that act as intermediates in various chemical reactions and are used in the production of coumarone-indene resins.
D009812 Odorants The volatile portions of chemical substances perceptible by the sense of smell. Odors,Aroma,Fragrance,Scents,Aromas,Fragrances,Odor,Odorant,Scent
D010476 Perfume A substance, extract, or preparation for diffusing or imparting an agreeable or attractive smell, especially a fluid containing fragrant natural oils extracted from flowers, woods, etc., or similar synthetic oils. (Random House Unabridged Dictionary, 2d ed)
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012486 Salmonella typhimurium A serotype of Salmonella enterica that is a frequent agent of Salmonella gastroenteritis in humans. It also causes PARATYPHOID FEVER. Salmonella typhimurium LT2
D054750 Ecotoxicology The study of ENVIRONMENTAL POLLUTION and the toxic effects of ENVIRONMENTAL POLLUTANTS on the ECOSYSTEM. The term was coined by Truhaut in 1969. Environmental Toxicology,Environmental Toxicologies,Toxicologies, Environmental,Toxicology, Environmental
D018570 Risk Assessment The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988) Assessment, Risk,Benefit-Risk Assessment,Risk Analysis,Risk-Benefit Assessment,Health Risk Assessment,Risks and Benefits,Analysis, Risk,Assessment, Benefit-Risk,Assessment, Health Risk,Assessment, Risk-Benefit,Benefit Risk Assessment,Benefit-Risk Assessments,Benefits and Risks,Health Risk Assessments,Risk Analyses,Risk Assessment, Health,Risk Assessments,Risk Benefit Assessment,Risk-Benefit Assessments
D023381 Endpoint Determination Establishment of the level of a quantifiable effect indicative of a biologic process. The evaluation is frequently to detect the degree of toxic or therapeutic effect. Endpoint Assay,End Point Assay,End Point Determination,Assay, End Point,Assay, Endpoint,Assays, End Point,Assays, Endpoint,Determination, Endpoint,Determinations, End Point,Determinations, Endpoint,End Point Assays,End Point Determinations,Endpoint Assays,Endpoint Determinations,Point Assay, End,Point Assays, End,Point Determinations, End

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