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The effects of ovine corticotropin releasing factor (o-CRF) on the secretions of ACTH, cortisol, dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEA-S) were studied in the healthy young and elderly male individuals. o-CRF caused significant elevations of plasma ACTH, cortisol and DHEA concentrations, in all subjects. Moreover, there were no significant differences in the time-dependent responses of plasma ACTH, cortisol and DHEA to o-CRF between the young and elderly male individuals. o-CRF showed no significant rise of plasma DHEA-S, in all subjects. We conclude that the pituitary-adrenal sensitivity to the hypothalamic CRF in the elderly does not change with aging.
M Ohashi, and
N Fujio, and
K Kato, and
H Nawata, and
H Ibayashi
May 1994,
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M Ohashi, and
N Fujio, and
K Kato, and
H Nawata, and
H Ibayashi
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M Ohashi, and
N Fujio, and
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H Ibayashi
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M Ohashi, and
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H Nawata, and
H Ibayashi
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M Ohashi, and
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H Ibayashi
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M Ohashi, and
N Fujio, and
K Kato, and
H Nawata, and
H Ibayashi
April 1963,
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M Ohashi, and
N Fujio, and
K Kato, and
H Nawata, and
H Ibayashi
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M Ohashi, and
N Fujio, and
K Kato, and
H Nawata, and
H Ibayashi
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M Ohashi, and
N Fujio, and
K Kato, and
H Nawata, and
H Ibayashi
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