Biomaterial Database

[Genetic differences in the eye manifestation of adjuvant arthritis in the rat. II. Histological investigations (author's transl)]. 1977

H Metzke, and S Tilgner

Hooded rats react to intracutaneous injections of complete Freund's adjuvant with an adjuvant disease, which is externally perceivable by massive polyarthritis, by skin and ear nodules, and by other known symptoms. In contrast to Wistar rats, however, they show no tendency to develop clinically or histologically provable eye manifestations such as an uveitis anterior (adjuvant uveitis). This fact has been connected with the genetic differences between the two strains of rats.

UI	MeSH Term	Description	Entries
D003433	Crosses, Genetic	Deliberate breeding of two different individuals that results in offspring that carry part of the genetic material of each parent. The parent organisms must be genetically compatible and may be from different varieties or closely related species.	Cross, Genetic,Genetic Cross,Genetic Crosses
D005132	Eye Manifestations	Ocular disorders attendant upon non-ocular disease or injury.	Eye Manifestation,Manifestation, Eye,Manifestations, Eye
D006168	Guinea Pigs	A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research.	Cavia,Cavia porcellus,Guinea Pig,Pig, Guinea,Pigs, Guinea
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D000917	Antibody Formation	The production of ANTIBODIES by proliferating and differentiated B-LYMPHOCYTES under stimulation by ANTIGENS.	Antibody Production,Antibody Response,Antibody Responses,Formation, Antibody,Production, Antibody,Response, Antibody,Responses, Antibody
D000941	Antigens	Substances that are recognized by the immune system and induce an immune reaction.	Antigen
D001168	Arthritis	Acute or chronic inflammation of JOINTS.	Oligoarthritis,Polyarthritis,Arthritides,Oligoarthritides,Polyarthritides
D001169	Arthritis, Experimental	ARTHRITIS that is induced in experimental animals. Immunological methods and infectious agents can be used to develop experimental arthritis models. These methods include injections of stimulators of the immune response, such as an adjuvant (ADJUVANTS, IMMUNOLOGIC) or COLLAGEN.	Adjuvant Arthritis,Arthritis, Adjuvant-Induced,Arthritis, Collagen-Induced,Arthritis, Adjuvant,Collagen Arthritis,Arthritides, Collagen,Arthritis, Collagen,Collagen Arthritides,Collagen-Induced Arthritides,Collagen-Induced Arthritis
D014605	Uveitis	Inflammation of part or all of the uvea, the middle (vascular) tunic of the eye, and commonly involving the other tunics (sclera and cornea, and the retina). (Dorland, 27th ed)	Uveitides
D051379	Mice	The common name for the genus Mus.	Mice, House,Mus,Mus musculus,Mice, Laboratory,Mouse,Mouse, House,Mouse, Laboratory,Mouse, Swiss,Mus domesticus,Mus musculus domesticus,Swiss Mice,House Mice,House Mouse,Laboratory Mice,Laboratory Mouse,Mice, Swiss,Swiss Mouse,domesticus, Mus musculus

Related Publications

H Metzke, and S Tilgner

[Genetic differences in the eye-manifestation of adjuvant arthritis in the rat. III. Crossbreeding experiments (author's transl)].

October 1977, Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology,

H Metzke, and S Tilgner

[Genetical differences in the eye-manifestation of adjuvant arthritis in the rat. I. Communication: investigations in three different strains (author's transl)].

December 1973, Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology,

H Metzke, and S Tilgner

[Chronic osteomyelitis as manifestation of adjuvant disease in the rat (author's transl)].

October 1974, Beitrage zur Pathologie,

H Metzke, and S Tilgner

[Histological investigations of cryptorchidism (author's transl)].

October 1973, Monatsschrift fur Kinderheilkunde,

H Metzke, and S Tilgner

[Intraoperative Histological Investigations in Gynaecology (author's transl)].

November 1976, Wiener klinische Wochenschrift,

H Metzke, and S Tilgner

[Adjuvant arthritis in rat: influence of oxonate and allopurinol (author's transl)].

April 1977, Experientia,