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Objectives: Condyloma acuminatum are the most common sexually transmitted diseases worldwide, and they are closely associated with human papillomavirus (HPV) infection. Urethral meatus is one of the places that warts occur. Many treatments for uretheral warts have limitations. In this study, we performed 5-aminolevulinic acid-photodynamic therapy (ALA-PDT) on patients and investigated the effectiveness of reducing HPV viral loads. Materials and Methods: In our study, 21 patients diagnosed with urethral condyloma acuminatum were included. After 4 h treatment of ALA, patients received PDT. Each patient received HPV test before every PDT cycle. The frequency of PDT was dependent on viral load changes. Results: All patients achieved complete clinical remission after the last session of ALA-PDT. There were significant differences in HPV viral loads between pretherapy and after one or three rounds of PDT treatment. Conclusions: ALA-PDT is a safe and effective method for treatment of condyloma acuminatum in urethra meatus. Dynamic monitoring of HPV viral loads can more objectively demonstrate the effectiveness and guide the treatment of PDT.
Jiajia Xie, and
Chunping Ao, and
Junpeng Li, and
Lifen Jiang, and
Hui Liu, and
Kang Zeng
November 2011,
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences,
Jiajia Xie, and
Chunping Ao, and
Junpeng Li, and
Lifen Jiang, and
Hui Liu, and
Kang Zeng
August 2023,
The journal of obstetrics and gynaecology research,
Jiajia Xie, and
Chunping Ao, and
Junpeng Li, and
Lifen Jiang, and
Hui Liu, and
Kang Zeng
March 2023,
Photodermatology, photoimmunology & photomedicine,
Jiajia Xie, and
Chunping Ao, and
Junpeng Li, and
Lifen Jiang, and
Hui Liu, and
Kang Zeng
June 2017,
Photodiagnosis and photodynamic therapy,
Jiajia Xie, and
Chunping Ao, and
Junpeng Li, and
Lifen Jiang, and
Hui Liu, and
Kang Zeng
December 2021,
Photodiagnosis and photodynamic therapy,
Jiajia Xie, and
Chunping Ao, and
Junpeng Li, and
Lifen Jiang, and
Hui Liu, and
Kang Zeng
December 2017,
Lasers in surgery and medicine,
Jiajia Xie, and
Chunping Ao, and
Junpeng Li, and
Lifen Jiang, and
Hui Liu, and
Kang Zeng
June 2022,
Photodiagnosis and photodynamic therapy,
Jiajia Xie, and
Chunping Ao, and
Junpeng Li, and
Lifen Jiang, and
Hui Liu, and
Kang Zeng
May 1993,
Hinyokika kiyo. Acta urologica Japonica,
Jiajia Xie, and
Chunping Ao, and
Junpeng Li, and
Lifen Jiang, and
Hui Liu, and
Kang Zeng
December 2022,
Photodiagnosis and photodynamic therapy,
Jiajia Xie, and
Chunping Ao, and
Junpeng Li, and
Lifen Jiang, and
Hui Liu, and
Kang Zeng
February 2012,
Zhonghua nan ke xue = National journal of andrology,
