Biomaterial Database

Isolation of an arenavirus closely related to Lassa virus from Mastomys natalensis in south-east Africa. 1977

H Wulff, and B M McIntosh, and D B Hamner, and K M Johnson

Five unidentified virus strains were recovered from the multimammate mouse ,Mastomys natalensis, during the course of studies on arbovirus infections in Mozambique. These agents were found to be morphologically and immunologically related to Lassa virus. Four of 19 sera from Mastomys captured in the study area had antibodies to both Lassa virus and one of the unidentified strains. Although not definitive, the differences noted in results of complement fixation and indirect immunofluorescent tests suggest that these viruses from south-east Africa are not identical to West African Lassa virus.

UI	MeSH Term	Description	Entries
D007836	Lassa virus	A species of ARENAVIRUS, part of the Old World Arenaviruses (ARENAVIRUSES, OLD WORLD), and the etiologic agent of LASSA FEVER. LASSA VIRUS is a common infective agent in humans in West Africa. Its natural host is the multimammate mouse Mastomys natalensis.
D001921	Brain	The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.	Encephalon
D000352	Africa, Northern	The geographical area of Africa comprising ALGERIA; EGYPT; LIBYA; MOROCCO and TUNISIA. It includes also the vast deserts and oases of the Sahara. It is often referred to as North Africa or the Maghreb.	Maghreb,Sahara,Maghrib,North Africa,Northern Africa
D000353	Africa, Southern	The geographical area of Africa comprising ANGOLA; BOTSWANA; LESOTHO; MALAWI; MOZAMBIQUE; NAMIBIA; SOUTH AFRICA; SWAZILAND; ZAMBIA; and ZIMBABWE.	Southern Africa
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D001116	Arenaviridae	A family of RNA viruses naturally infecting rodents and consisting of one genus (ARENAVIRUS) with two groups: Old World Arenaviruses (ARENAVIRUSES, OLD WORLD) and New World Arenaviruses (ARENAVIRUSES, NEW WORLD). Infection in rodents is persistent and silent. Vertical transmission is through milk-, saliva-, or urine-borne routes. Horizontal transmission to humans, monkeys, and other animals is important.	Mammarenavirus,Reptarenavirus,Mammarenaviruses,Reptarenaviruses
D051379	Mice	The common name for the genus Mus.	Mice, House,Mus,Mus musculus,Mice, Laboratory,Mouse,Mouse, House,Mouse, Laboratory,Mouse, Swiss,Mus domesticus,Mus musculus domesticus,Swiss Mice,House Mice,House Mouse,Laboratory Mice,Laboratory Mouse,Mice, Swiss,Swiss Mouse,domesticus, Mus musculus