BIOMAT Database Logo BIOMAT Database Logo

[Monoclonal antibodies ICO-20 against human thymocyte antigen T10]. 1988

A Iu Baryshnikov, and O V Korotkova, and N N Tupitsyn, and I V Dubinkin, and E N Sholokhova

Monoclonal antibodies (Mab) Ig G2a isotypes reacting in indirect immunofluorescence assay with 68.7 +/- 4.1% of thymocytes, 7% of T-cells and not determining the antigen on other blood cells were obtained. Mab ICO-20 reacted in complement-dependent cytotoxic test. The antigen was expressed on colony-forming cells of granulocyte-macrophage row. Mab ICO-20 reaction with 100% of thymocytes was defined by flow cytometry. Antigen molecular mass is 45000 Dalton. The antigen was expressed on blast cells of patients with ALL and AML. Mab ICO-20 reaction was more more often with T-cell ALL.

UI MeSH Term Description Entries
D008562 Membrane Glycoproteins Glycoproteins found on the membrane or surface of cells. Cell Surface Glycoproteins,Surface Glycoproteins,Cell Surface Glycoprotein,Membrane Glycoprotein,Surface Glycoprotein,Glycoprotein, Cell Surface,Glycoprotein, Membrane,Glycoprotein, Surface,Glycoproteins, Cell Surface,Glycoproteins, Membrane,Glycoproteins, Surface,Surface Glycoprotein, Cell,Surface Glycoproteins, Cell
D011233 Precipitin Tests Serologic tests in which a positive reaction manifested by visible CHEMICAL PRECIPITATION occurs when a soluble ANTIGEN reacts with its precipitins, i.e., ANTIBODIES that can form a precipitate. Precipitin Test,Test, Precipitin,Tests, Precipitin
D005455 Fluorescent Antibody Technique Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy. Antinuclear Antibody Test, Fluorescent,Coon's Technique,Fluorescent Antinuclear Antibody Test,Fluorescent Protein Tracing,Immunofluorescence Technique,Coon's Technic,Fluorescent Antibody Technic,Immunofluorescence,Immunofluorescence Technic,Antibody Technic, Fluorescent,Antibody Technics, Fluorescent,Antibody Technique, Fluorescent,Antibody Techniques, Fluorescent,Coon Technic,Coon Technique,Coons Technic,Coons Technique,Fluorescent Antibody Technics,Fluorescent Antibody Techniques,Fluorescent Protein Tracings,Immunofluorescence Technics,Immunofluorescence Techniques,Protein Tracing, Fluorescent,Protein Tracings, Fluorescent,Technic, Coon's,Technic, Fluorescent Antibody,Technic, Immunofluorescence,Technics, Fluorescent Antibody,Technics, Immunofluorescence,Technique, Coon's,Technique, Fluorescent Antibody,Technique, Immunofluorescence,Techniques, Fluorescent Antibody,Techniques, Immunofluorescence,Tracing, Fluorescent Protein,Tracings, Fluorescent Protein
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006825 Hybridomas Cells artificially created by fusion of activated lymphocytes with neoplastic cells. The resulting hybrid cells are cloned and produce pure MONOCLONAL ANTIBODIES or T-cell products, identical to those produced by the immunologically competent parent cell. Hybridoma
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000911 Antibodies, Monoclonal Antibodies produced by a single clone of cells. Monoclonal Antibodies,Monoclonal Antibody,Antibody, Monoclonal
D000943 Antigens, Differentiation Antigens expressed primarily on the membranes of living cells during sequential stages of maturation and differentiation. As immunologic markers they have high organ and tissue specificity and are useful as probes in studies of normal cell development as well as neoplastic transformation. Differentiation Antigen,Differentiation Antigens,Differentiation Antigens, Hairy Cell Leukemia,Differentiation Marker,Differentiation Markers,Leu Antigen,Leu Antigens,Marker Antigen,Marker Antigens,Markers, Differentiation,Antigen, Differentiation,Antigen, Leu,Antigen, Marker,Antigens, Leu,Antigens, Marker,Marker, Differentiation
D013601 T-Lymphocytes Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen. T Cell,T Lymphocyte,T-Cells,Thymus-Dependent Lymphocytes,Cell, T,Cells, T,Lymphocyte, T,Lymphocyte, Thymus-Dependent,Lymphocytes, T,Lymphocytes, Thymus-Dependent,T Cells,T Lymphocytes,T-Cell,T-Lymphocyte,Thymus Dependent Lymphocytes,Thymus-Dependent Lymphocyte
D015703 Antigens, CD Differentiation antigens residing on mammalian leukocytes. CD stands for cluster of differentiation, which refers to groups of monoclonal antibodies that show similar reactivity with certain subpopulations of antigens of a particular lineage or differentiation stage. The subpopulations of antigens are also known by the same CD designation. CD Antigen,Cluster of Differentiation Antigen,Cluster of Differentiation Marker,Differentiation Antigens, Leukocyte, Human,Leukocyte Differentiation Antigens, Human,Cluster of Differentiation Antigens,Cluster of Differentiation Markers,Antigen Cluster, Differentiation,Antigen, CD,CD Antigens,Differentiation Antigen Cluster,Differentiation Marker Cluster,Marker Cluster, Differentiation

Related Publications

A Iu Baryshnikov, and O V Korotkova, and N N Tupitsyn, and I V Dubinkin, and E N Sholokhova
[ICO-166 monoclonal antibodies against the CD45RA antigen].
July 1993, Biulleten' eksperimental'noi biologii i meditsiny,
A Iu Baryshnikov, and O V Korotkova, and N N Tupitsyn, and I V Dubinkin, and E N Sholokhova
[Monoclonal antibodies against human differentiated thymocyte antigens].
September 1984, Biulleten' eksperimental'noi biologii i meditsiny,
A Iu Baryshnikov, and O V Korotkova, and N N Tupitsyn, and I V Dubinkin, and E N Sholokhova
[Monoclonal antibodies of the ICO series against differentiation antigens of human lymphocytes].
August 1990, Gematologiia i transfuziologiia,
A Iu Baryshnikov, and O V Korotkova, and N N Tupitsyn, and I V Dubinkin, and E N Sholokhova
[Standardization of ICO-G2 monoclonal antibodies against X-hapten].
January 1989, Eksperimental'naia onkologiia,
A Iu Baryshnikov, and O V Korotkova, and N N Tupitsyn, and I V Dubinkin, and E N Sholokhova
[Monoclonal antibody ICO-92 against the transferrin receptor (antigen CD71)].
February 1993, Doklady Akademii nauk,
A Iu Baryshnikov, and O V Korotkova, and N N Tupitsyn, and I V Dubinkin, and E N Sholokhova
[Production and characterisation of monoclonal antibodies ICO-160 against antigen CD95(Fas/APO-1) mediating apoptosis].
June 1998, Biulleten' eksperimental'noi biologii i meditsiny,
A Iu Baryshnikov, and O V Korotkova, and N N Tupitsyn, and I V Dubinkin, and E N Sholokhova
[Monoclonal antibodies of the ICO series].
December 1988, Gematologiia i transfuziologiia,
A Iu Baryshnikov, and O V Korotkova, and N N Tupitsyn, and I V Dubinkin, and E N Sholokhova
[Standardization of ICO-1 monoclonal antibodies against monomorphic Ia-like (Dr) antigens].
January 1987, Eksperimental'naia onkologiia,
A Iu Baryshnikov, and O V Korotkova, and N N Tupitsyn, and I V Dubinkin, and E N Sholokhova
[ICO-1 monoclonal antibodies against the constant region of Ia-like (Dr) antigens].
January 1984, Eksperimental'naia onkologiia,
A Iu Baryshnikov, and O V Korotkova, and N N Tupitsyn, and I V Dubinkin, and E N Sholokhova
[ICO-63 monoclonal antibodies to the differentiation antigen of hemopoietic cells suitable for immunophenotyping of human solid tumors].
January 1989, Eksperimental'naia onkologiia,
Copied contents to your clipboard!