| D007249 |
Inflammation |
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. |
Innate Inflammatory Response,Inflammations,Inflammatory Response, Innate,Innate Inflammatory Responses |
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| D008262 |
Macrophage Activation |
The process of altering the morphology and functional activity of macrophages so that they become avidly phagocytic. It is initiated by lymphokines, such as the macrophage activation factor (MAF) and the macrophage migration-inhibitory factor (MMIF), immune complexes, C3b, and various peptides, polysaccharides, and immunologic adjuvants. |
Activation, Macrophage,Activations, Macrophage,Macrophage Activations |
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| D008264 |
Macrophages |
The relatively long-lived phagocytic cell of mammalian tissues that are derived from blood MONOCYTES. Main types are PERITONEAL MACROPHAGES; ALVEOLAR MACROPHAGES; HISTIOCYTES; KUPFFER CELLS of the liver; and OSTEOCLASTS. They may further differentiate within chronic inflammatory lesions to EPITHELIOID CELLS or may fuse to form FOREIGN BODY GIANT CELLS or LANGHANS GIANT CELLS. (from The Dictionary of Cell Biology, Lackie and Dow, 3rd ed.) |
Bone Marrow-Derived Macrophages,Monocyte-Derived Macrophages,Macrophage,Macrophages, Monocyte-Derived,Bone Marrow Derived Macrophages,Bone Marrow-Derived Macrophage,Macrophage, Bone Marrow-Derived,Macrophage, Monocyte-Derived,Macrophages, Bone Marrow-Derived,Macrophages, Monocyte Derived,Monocyte Derived Macrophages,Monocyte-Derived Macrophage |
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| D010743 |
Phospholipids |
Lipids containing one or more phosphate groups, particularly those derived from either glycerol (phosphoglycerides see GLYCEROPHOSPHOLIPIDS) or sphingosine (SPHINGOLIPIDS). They are polar lipids that are of great importance for the structure and function of cell membranes and are the most abundant of membrane lipids, although not stored in large amounts in the system. |
Phosphatides,Phospholipid |
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| D005992 |
Glycerol-3-Phosphate O-Acyltransferase |
An enzyme that transfers acyl groups from acyl-CoA to glycerol-3-phosphate to form monoglyceride phosphates. It acts only with CoA derivatives of fatty acids of chain length above C-10. Also forms diglyceride phosphates. EC 2.3.1.15. |
Glycerolphosphate Acyltransferase,Stearyl-CoA Glycerophosphate Transstearylase,Acyl-CoA Sn-Glycerol-3-Phosphate-O-Acyltransferase,Glycerophosphate Acyltransferase,Acyl CoA Sn Glycerol 3 Phosphate O Acyltransferase,Acyltransferase, Glycerolphosphate,Acyltransferase, Glycerophosphate,Glycerol 3 Phosphate O Acyltransferase,Glycerophosphate Transstearylase, Stearyl-CoA,O-Acyltransferase, Glycerol-3-Phosphate,Sn-Glycerol-3-Phosphate-O-Acyltransferase, Acyl-CoA,Stearyl CoA Glycerophosphate Transstearylase,Transstearylase, Stearyl-CoA Glycerophosphate |
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| D000818 |
Animals |
Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. |
Animal,Metazoa,Animalia |
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| D014280 |
Triglycerides |
An ester formed from GLYCEROL and three fatty acid groups. |
Triacylglycerol,Triacylglycerols,Triglyceride |
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| D050155 |
Lipogenesis |
De novo fat synthesis in the body. This includes the synthetic processes of FATTY ACIDS and subsequent TRIGLYCERIDES in the LIVER and the ADIPOSE TISSUE. Lipogenesis is regulated by numerous factors, including nutritional, hormonal, and genetic elements. |
Lipogeneses |
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| D051103 |
1-Acylglycerol-3-Phosphate O-Acyltransferase |
An enzyme that catalyzes the acyl group transfer of ACYL COA to 1-acyl-sn-glycerol 3-phosphate to generate 1,2-diacyl-sn-glycerol 3-phosphate. This enzyme has alpha, beta, gamma, delta and epsilon subunits. |
1-AGP-Acyltransferase,1-Acylglycerol Phosphate Acyltransferase 2,1-Acylglycerophosphate Acyltransferase,1-Palmitylglycerol 3-Phosphate Acyltransferase,Acyl CoA-1-Acyl-Syn-Glycerol-3-Phosphate O-Acyltransferase,Acyl CoA-Monoacylglycerophosphateacyltransferase,Acyl Coenzyme A-Monacylglycerophosphateacyltransferase,1 AGP Acyltransferase,1 Acylglycerol 3 Phosphate O Acyltransferase,1 Acylglycerol Phosphate Acyltransferase 2,1 Acylglycerophosphate Acyltransferase,1 Palmitylglycerol 3 Phosphate Acyltransferase,3-Phosphate Acyltransferase, 1-Palmitylglycerol,A-Monacylglycerophosphateacyltransferase, Acyl Coenzyme,Acyl CoA 1 Acyl Syn Glycerol 3 Phosphate O Acyltransferase,Acyl CoA Monoacylglycerophosphateacyltransferase,Acyl Coenzyme A Monacylglycerophosphateacyltransferase,Acyltransferase, 1-Acylglycerophosphate,Acyltransferase, 1-Palmitylglycerol 3-Phosphate,CoA-1-Acyl-Syn-Glycerol-3-Phosphate O-Acyltransferase, Acyl,CoA-Monoacylglycerophosphateacyltransferase, Acyl,Coenzyme A-Monacylglycerophosphateacyltransferase, Acyl,O-Acyltransferase, 1-Acylglycerol-3-Phosphate,O-Acyltransferase, Acyl CoA-1-Acyl-Syn-Glycerol-3-Phosphate |
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| D051379 |
Mice |
The common name for the genus Mus. |
Mice, House,Mus,Mus musculus,Mice, Laboratory,Mouse,Mouse, House,Mouse, Laboratory,Mouse, Swiss,Mus domesticus,Mus musculus domesticus,Swiss Mice,House Mice,House Mouse,Laboratory Mice,Laboratory Mouse,Mice, Swiss,Swiss Mouse,domesticus, Mus musculus |
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