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The in vitro treatment of the mouse spleen cells immunized by the ram erythrocytes with the rabbit and mouse sera against the thermoaggregated mouse immunoglobulins resulted in the inhibition of antigen binding receptors of rosette forming cells. The mouse serum, unlike the rabbit one, induced the inactivation of receptors in rosette forming lymphocytes both in the non-immune and immune mice on the 8th day after the antigenic stimulation. The treatment of bone marrow cells from the intact mice with these sera increased insignificantly the number of hemopoietic colonies in the spleens of lethally irradiated syngenic recipients and stimulated markedly the migration of spleen cells. This may be due both to the direct effect of these sera and to their mediated (through the humoral factor) influence. The inactivation of antigen binding receptors in the spleen rosette forming cells suggests the presence of immunoglobulins on the membrane of B-lymphocytes in the aggregated state or in the form of antigen--antibody complexes.
V V Khorobrykh, and
D R Kaulen, and
T A Golovanova, and
E B Mysiakin, and
D P Piatykhina
December 1977,
Biulleten' eksperimental'noi biologii i meditsiny,
V V Khorobrykh, and
D R Kaulen, and
T A Golovanova, and
E B Mysiakin, and
D P Piatykhina
August 1971,
Journal of immunology (Baltimore, Md. : 1950),
V V Khorobrykh, and
D R Kaulen, and
T A Golovanova, and
E B Mysiakin, and
D P Piatykhina
April 1981,
Biulleten' eksperimental'noi biologii i meditsiny,
V V Khorobrykh, and
D R Kaulen, and
T A Golovanova, and
E B Mysiakin, and
D P Piatykhina
May 1978,
Biulleten' eksperimental'noi biologii i meditsiny,
V V Khorobrykh, and
D R Kaulen, and
T A Golovanova, and
E B Mysiakin, and
D P Piatykhina
July 1980,
Biulleten' eksperimental'noi biologii i meditsiny,
V V Khorobrykh, and
D R Kaulen, and
T A Golovanova, and
E B Mysiakin, and
D P Piatykhina
November 1979,
Bollettino dell'Istituto sieroterapico milanese,
V V Khorobrykh, and
D R Kaulen, and
T A Golovanova, and
E B Mysiakin, and
D P Piatykhina
January 1977,
Ontogenez,
V V Khorobrykh, and
D R Kaulen, and
T A Golovanova, and
E B Mysiakin, and
D P Piatykhina
January 1974,
Progress in clinical immunology,
V V Khorobrykh, and
D R Kaulen, and
T A Golovanova, and
E B Mysiakin, and
D P Piatykhina
November 1979,
Biulleten' eksperimental'noi biologii i meditsiny,
V V Khorobrykh, and
D R Kaulen, and
T A Golovanova, and
E B Mysiakin, and
D P Piatykhina
April 1979,
Clinical immunology and immunopathology,
