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A study of peripheral blood lymphocyte populations in 27 children with Hodgkin's disease (HD) and 13 age-matched control subjects is presented. The absolute numbers and percentages of T and B lymphocytes identified by their surface marker characteristics were determined. In addition, in 13 HD children the percentages of T and B lymphocytes were estimated in the spleens removed at staging laparotomy. No differences were observed between the total peripheral blood lymphocyte counts of HD and control children, and we found no evidence of progressive lymphopenia with advancing stages of the disease. No decrease in the numbers of peripheral blood T lymphocytes was seen in this group of HD children. In contrast, the proportions and absolute numbers of B lymphocytes tended to be significantly lower in the children with HD than in the control subjects. In 9 of the 13 spleens studied high percentages of T lymphocytes were seen; low percentage of B lymphocytes were found in all spleens examined.
M de Sousa, and
C T Tan, and
F P Siegal, and
D A Filippa, and
R Tan, and
R A Good
February 1977,
Haematologica,
M de Sousa, and
C T Tan, and
F P Siegal, and
D A Filippa, and
R Tan, and
R A Good
July 1976,
Polskie Archiwum Medycyny Wewnetrznej,
M de Sousa, and
C T Tan, and
F P Siegal, and
D A Filippa, and
R Tan, and
R A Good
March 1975,
Lancet (London, England),
M de Sousa, and
C T Tan, and
F P Siegal, and
D A Filippa, and
R Tan, and
R A Good
January 1976,
Acta haematologica,
M de Sousa, and
C T Tan, and
F P Siegal, and
D A Filippa, and
R Tan, and
R A Good
February 1980,
Clinical immunology and immunopathology,
M de Sousa, and
C T Tan, and
F P Siegal, and
D A Filippa, and
R Tan, and
R A Good
February 1983,
Nihon juigaku zasshi. The Japanese journal of veterinary science,
M de Sousa, and
C T Tan, and
F P Siegal, and
D A Filippa, and
R Tan, and
R A Good
January 1979,
Neoplasma,
M de Sousa, and
C T Tan, and
F P Siegal, and
D A Filippa, and
R Tan, and
R A Good
January 1979,
Endokrynologia Polska,
M de Sousa, and
C T Tan, and
F P Siegal, and
D A Filippa, and
R Tan, and
R A Good
January 1978,
Neoplasma,
M de Sousa, and
C T Tan, and
F P Siegal, and
D A Filippa, and
R Tan, and
R A Good
January 1987,
Folia medica Cracoviensia,
