-transparent.png){kind=logo}
The acute effects of luteinizing hormone releasing hormone (LHRH) on the release of prolactin (PRL) were investigated in 12 normal cycling women and 42 women with various menstrual disorders. LHRH (100 micrograms) was bolusly injected intramuscularly and PRL levels were measured immediately before the injection and at 30 minutes and 60 minutes after the injection. LHRH elicited an increase of more than 25% in PRL levels in 15 cases (27.8%) at both 30 minutes and 60 minutes after the injection, whereas PRL levels were decreased by more than 25% in 7 cases (13.0%). The PRL response to LHRH seemed to be related to basal PRL levels. Especially when the PRL concentration was 20 ng/ml or more, LHRH decreased PRL levels in 7 cases out of 16. On the other hand, LHRH increased PRL levels in the majority of cases with a PRL concentration less than 20 ng/ml. In conclusion, the LHRH injection occasionally alters PRL levels in either a positive or negative manner, depending upon the basal PRL levels.
K Kugu, and
Y Taketani, and
M Mizuno
August 2001,
Internal medicine (Tokyo, Japan),
K Kugu, and
Y Taketani, and
M Mizuno
June 1988,
The International journal of neuroscience,
K Kugu, and
Y Taketani, and
M Mizuno
May 1981,
The Journal of clinical endocrinology and metabolism,
K Kugu, and
Y Taketani, and
M Mizuno
June 1986,
Nihon Naibunpi Gakkai zasshi,
K Kugu, and
Y Taketani, and
M Mizuno
October 1982,
Endocrinology,
K Kugu, and
Y Taketani, and
M Mizuno
December 1985,
Experimental and clinical endocrinology,
K Kugu, and
Y Taketani, and
M Mizuno
March 1986,
Neurology,
K Kugu, and
Y Taketani, and
M Mizuno
December 1976,
Endocrinologia japonica,
K Kugu, and
Y Taketani, and
M Mizuno
October 1981,
American journal of obstetrics and gynecology,
K Kugu, and
Y Taketani, and
M Mizuno
December 1978,
British journal of obstetrics and gynaecology,
