-transparent.png){kind=logo}
For the first time, segregation of three common PiM alleles in family material is verified by application of separator isoelectric focusing. A new nomenclature system for the Pi M subtypes is used, whereby the common subtypes are designated according to their physicochemical properties; the most anodal type is called Pi M1, the intermediary one Pi M2, and the most cathodal variant Pi M3 (previously called Pi M2). Pi gene frequencies from Finnish, Dutch and Black populations are presented. The PiM2 allele was rather high in Finns (0.12) but low (0.04) in the West African Bozo. The PiM3 was found with a frequency of 0.13 in Dutch, 0.08 in Finns and 0.02 in Bozo. A previous Finnish sample was retested with the new subtyping method and the six-subtype distribution was found to be in good Hardy-Weinberg equilibrium. The validity of the Pi polymorphism for population genetics, linkage analysis and parentage testing is discussed.
R R Frants, and
A W Eriksson
March 1988,
Electrophoresis,
R R Frants, and
A W Eriksson
January 1986,
Journal - Forensic Science Society,
R R Frants, and
A W Eriksson
January 1980,
Zeitschrift fur Rechtsmedizin. Journal of legal medicine,
R R Frants, and
A W Eriksson
October 1990,
Clinical chemistry,
R R Frants, and
A W Eriksson
June 1979,
Jinrui idengaku zasshi. The Japanese journal of human genetics,
R R Frants, and
A W Eriksson
January 1985,
Human genetics,
R R Frants, and
A W Eriksson
January 1986,
Human heredity,
R R Frants, and
A W Eriksson
January 1984,
Critical reviews in clinical laboratory sciences,
R R Frants, and
A W Eriksson
September 1989,
Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao,
R R Frants, and
A W Eriksson
June 1995,
The quarterly journal of nuclear medicine : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR),
