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Two subpopulation of circulating human T cells forming rosettes with neuraminidase-treated sheep erythrocytes were purified on the basis of the presence of receptors for IgG (TG cells) or for IgM (TM cells), and were shown to have distinguishing morphological and histochemical characteristics. TM cells had the general features of typical small- or medium-sized lymphocytes; most were easily identifiable by distinctive cytoplasmic accumulations, usually one and sometimes two large spots, of nonspecific acid esterase activity. The release of the vesicular contents on short-term culture of TG cells was inhibited by cytochalasin B. Definition of these distinguishing characteristics of TM and TG cells provides a basis for practical enumeration of these functionally distinct subpopulations of human T cells. Some of the TG cells were capable of endocytosis of IgG antibody-coated erythrocytes.
C E Grossi, and
S R Webb, and
A Zicca, and
P M Lydyard, and
L Moretta, and
M C Mingari, and
M D Cooper
September 1979,
Clinical and experimental immunology,
C E Grossi, and
S R Webb, and
A Zicca, and
P M Lydyard, and
L Moretta, and
M C Mingari, and
M D Cooper
July 2005,
Nihon rinsho. Japanese journal of clinical medicine,
C E Grossi, and
S R Webb, and
A Zicca, and
P M Lydyard, and
L Moretta, and
M C Mingari, and
M D Cooper
November 1999,
Nihon rinsho. Japanese journal of clinical medicine,
C E Grossi, and
S R Webb, and
A Zicca, and
P M Lydyard, and
L Moretta, and
M C Mingari, and
M D Cooper
June 2010,
Nihon rinsho. Japanese journal of clinical medicine,
C E Grossi, and
S R Webb, and
A Zicca, and
P M Lydyard, and
L Moretta, and
M C Mingari, and
M D Cooper
January 1981,
American journal of reproductive immunology : AJRI : official journal of the American Society for the Immunology of Reproduction and the International Coordination Committee for Immunology of Reproduction,
C E Grossi, and
S R Webb, and
A Zicca, and
P M Lydyard, and
L Moretta, and
M C Mingari, and
M D Cooper
August 1980,
Clinical and experimental immunology,
C E Grossi, and
S R Webb, and
A Zicca, and
P M Lydyard, and
L Moretta, and
M C Mingari, and
M D Cooper
January 1984,
Laboratornoe delo,
C E Grossi, and
S R Webb, and
A Zicca, and
P M Lydyard, and
L Moretta, and
M C Mingari, and
M D Cooper
August 1980,
Clinical and experimental immunology,
C E Grossi, and
S R Webb, and
A Zicca, and
P M Lydyard, and
L Moretta, and
M C Mingari, and
M D Cooper
May 1979,
European journal of immunology,
C E Grossi, and
S R Webb, and
A Zicca, and
P M Lydyard, and
L Moretta, and
M C Mingari, and
M D Cooper
January 1981,
Immunological reviews,
