A comprehensive approach to developing and maintaining drug-free schools and communities is discussed. Five sequential phases, needs assessment, planning, implementation, evaluation, and dissemination, are described. An effective implementation program meets the needs of students at various stages of drug use and abuse. Prevention strategies are effective with students who have only experimented or never used drugs, while early intervention strategies are most effective for students who have a more regular use pattern. Chemically dependent students need referral for treatment at a community social agency. After treatment and rehabilitation, returning to a supportive aftercare school program proves most effective. The approach described in this article advocates a team effort including well-trained school core teams collaborating with parents and community representatives from law enforcement, social agencies, business, religious groups, and the media.