Biomaterial Database

Mutagenic activity in drinking water prepared from groundwater: a survey of ten cities in The Netherlands. 1988

H J Kool, and C F van Kreyl

Stichting Waterlaboratorium Oost, Doetinchem, The Netherlands.

A survey of the mutagenic activity (Ames Salmonella/microsome assay) in drinking water prepared from groundwater in 10 cities of The Netherlands is presented. Mutagenic activity with strain TA98 with S-9 mix was found in the drinking water of six cities. There are strong indications that this mutagenic activity is caused by organics of natural origin. In the drinking water of three cities, trichloroethane, trichloroethene and tetrachloroethene were detected, which indicates that in these water-catchment areas organic pollutants have reached groundwater.

UI	MeSH Term	Description	Entries
D009152	Mutagenicity Tests	Tests of chemical substances and physical agents for mutagenic potential. They include microbial, insect, mammalian cell, and whole animal tests.	Genetic Toxicity Tests,Genotoxicity Tests,Mutagen Screening,Tests, Genetic Toxicity,Toxicity Tests, Genetic,Genetic Toxicity Test,Genotoxicity Test,Mutagen Screenings,Mutagenicity Test,Screening, Mutagen,Screenings, Mutagen,Test, Genotoxicity,Tests, Genotoxicity,Toxicity Test, Genetic
D009153	Mutagens	Chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes.	Clastogen,Clastogens,Genotoxin,Genotoxins,Mutagen
D009426	Netherlands	Country located in EUROPE. It is bordered by the NORTH SEA, BELGIUM, and GERMANY. Constituent areas are Aruba, Curacao, and Sint Maarten, formerly included in the NETHERLANDS ANTILLES.	Holland,Kingdom of the Netherlands
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012486	Salmonella typhimurium	A serotype of Salmonella enterica that is a frequent agent of Salmonella gastroenteritis in humans. It also causes PARATYPHOID FEVER.	Salmonella typhimurium LT2
D014505	Urban Population	The inhabitants of a city or town, including metropolitan areas and suburban areas.	Urban Residence,Urban Spatial Distribution,Distribution, Urban Spatial,Distributions, Urban Spatial,Population, Urban,Populations, Urban,Residence, Urban,Urban Populations,Urban Residences,Urban Spatial Distributions
D014881	Water Supply	Means or process of supplying water (as for a community) usually including reservoirs, tunnels, and pipelines and often the watershed from which the water is ultimately drawn. (Webster, 3d ed)	Supplies, Water,Supply, Water,Water Supplies