Acquired pachydermatoglyphy. A cutaneous sign of internal malignancy. 1988

R M Pujol, and L Puig, and J M García-Marques, and J M de Moragas
Department of Dermatology, Hospital Sant Pau, Barcelona, Spain.

A 70-year-old man with hypertrophic osteoartropathy secondary to a squamous cell carcinoma of the lung presented a distinctive pattern of late-onset bilateral palmar keratoderma. A yellowish rugose appearance with accentuation of normal ridges and sulci (pachydermatoglyphy) involving the palms was observed. The differential diagnosis and the clinical relevance of acquired pachydermatoglyphy as a cutaneous marker of internal malignancy are discussed.

UI MeSH Term Description Entries
D008209 Lymphedema Edema due to obstruction of lymph vessels or disorders of the lymph nodes. Milroy's Disease,Congenital Familial Lymphedema,Congenital Hereditary Lymphedema,Early Onset Lymphedema,Hereditary Lymphedema,Hereditary Lymphedema 1,Hereditary Lymphedema Type I,Lymphedema, Early-Onset,Lymphedema, Hereditary, Ia,Milroy Disease,Nonne-Milroy Disease,Nonne-Milroy Lymphedema,Nonne-Milroy-Meige Disease,Primary Congenital Lymphedema,Congenital Hereditary Lymphedemas,Congenital Lymphedema, Primary,Congenital Lymphedemas, Primary,Early Onset Lymphedemas,Early-Onset Lymphedema,Early-Onset Lymphedemas,Hereditary Lymphedema 1s,Hereditary Lymphedema, Congenital,Hereditary Lymphedemas,Hereditary Lymphedemas, Congenital,Lymphedema, Congenital Hereditary,Lymphedema, Early Onset,Lymphedema, Hereditary,Lymphedema, Nonne-Milroy,Lymphedema, Primary Congenital,Lymphedemas,Lymphedemas, Congenital Hereditary,Lymphedemas, Early Onset,Lymphedemas, Early-Onset,Lymphedemas, Hereditary,Lymphedemas, Primary Congenital,Milroys Disease,Nonne Milroy Disease,Nonne Milroy Lymphedema,Nonne Milroy Meige Disease,Primary Congenital Lymphedemas
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D010004 Osteoarthropathy, Primary Hypertrophic A condition chiefly characterized by thickening of the skin of the head and distal extremities, deep folds and furrows of the skin of the forehead, cheeks, and scalp, SEBORRHEA; HYPERHIDROSIS; periostosis of the long bones, digital clubbing, and spadelike enlargement of the hands and feet. It is more prevalent in the male, and is usually first evident during adolescence. Inheritance is primarily autosomal recessive, but an autosomal dominant form exists. Pachydermoperiostosis,Acropachy, Hereditary,Clubbing of Digits,Cranioosteoarthropathy,Currarino Idiopathic Osteoarthropathy,Digital Clubbing, Isolated Congenital,Familial Idiopathic Osteoarthropathy Of Childhood,Hypertrophic Osteoarthropathy, Primary, Autosomal Dominant,Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive,Idiopathic Hypertrophic Osteoarthropathy,Pachydermoperiostosis, Autosomal Dominant,Pachydermoperiostosis, Autosomal Recessive,Primary Hypertrophic Osteoarthropathy, Autosomal Dominant,Touraine-Solente-Gole Syndrome,Acropachies, Hereditary,Autosomal Dominant Pachydermoperiostoses,Autosomal Dominant Pachydermoperiostosis,Autosomal Recessive Pachydermoperiostosis,Cranioosteoarthropathies,Hereditary Acropachies,Hereditary Acropachy,Hypertrophic Osteoarthropathy, Idiopathic,Hypertrophic Osteoarthropathy, Primary,Osteoarthropathy, Currarino Idiopathic,Osteoarthropathy, Idiopathic Hypertrophic,Pachydermoperiostoses, Autosomal Dominant,Primary Hypertrophic Osteoarthropathy,Recessive Pachydermoperiostosis, Autosomal,Touraine Solente Gole Syndrome
D001984 Bronchial Neoplasms Tumors or cancer of the BRONCHI. Neoplasms, Bronchial,Bronchial Neoplasm,Neoplasm, Bronchial
D002294 Carcinoma, Squamous Cell A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed) Carcinoma, Epidermoid,Carcinoma, Planocellular,Carcinoma, Squamous,Squamous Cell Carcinoma,Carcinomas, Epidermoid,Carcinomas, Planocellular,Carcinomas, Squamous,Carcinomas, Squamous Cell,Epidermoid Carcinoma,Epidermoid Carcinomas,Planocellular Carcinoma,Planocellular Carcinomas,Squamous Carcinoma,Squamous Carcinomas,Squamous Cell Carcinomas
D003878 Dermatoglyphics The study of the patterns of ridges of the skin of the fingers, palms, toes, and soles. Fingerprints,Plantar Prints,Fingerprint,Plantar Print,Print, Plantar,Prints, Plantar
D003937 Diagnosis, Differential Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures. Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D004604 Elephantiasis Hypertrophy and thickening of tissues from causes other than filarial infection, the latter being described as ELEPHANTIASIS, FILARIAL. Bigfoot Disease,Elephantiasis Nostras Verrucosa,Endemic Elephantiasis,Endemic Non-Filarial Elephantiasis,Lymphostatic Verrucosis,Microcrystal Disease,Mossy foot,Podoconiosis,Bigfoot Diseases,Disease, Bigfoot,Disease, Microcrystal,Diseases, Bigfoot,Diseases, Microcrystal,Elephantiases,Elephantiases, Endemic,Elephantiases, Endemic Non-Filarial,Elephantiasis Nostras Verrucosas,Elephantiasis, Endemic,Elephantiasis, Endemic Non-Filarial,Endemic Elephantiases,Endemic Non Filarial Elephantiasis,Endemic Non-Filarial Elephantiases,Lymphostatic Verrucoses,Microcrystal Diseases,Mossy foots,Non-Filarial Elephantiases, Endemic,Non-Filarial Elephantiasis, Endemic,Nostras Verrucosa, Elephantiasis,Nostras Verrucosas, Elephantiasis,Podoconioses,Verrucosa, Elephantiasis Nostras,Verrucosas, Elephantiasis Nostras,Verrucoses, Lymphostatic,Verrucosis, Lymphostatic,foot, Mossy,foots, Mossy
D005260 Female Females

Related Publications

R M Pujol, and L Puig, and J M García-Marques, and J M de Moragas
October 1979, Annales de dermatologie et de venereologie,
R M Pujol, and L Puig, and J M García-Marques, and J M de Moragas
January 2007, Indian journal of dermatology, venereology and leprology,
R M Pujol, and L Puig, and J M García-Marques, and J M de Moragas
January 1992, Dermatology (Basel, Switzerland),
R M Pujol, and L Puig, and J M García-Marques, and J M de Moragas
January 1985, International journal of dermatology,
R M Pujol, and L Puig, and J M García-Marques, and J M de Moragas
November 1995, International journal of dermatology,
R M Pujol, and L Puig, and J M García-Marques, and J M de Moragas
August 1996, The Australasian journal of dermatology,
R M Pujol, and L Puig, and J M García-Marques, and J M de Moragas
January 1970, Archives of dermatology,
R M Pujol, and L Puig, and J M García-Marques, and J M de Moragas
November 1969, Cancer,
R M Pujol, and L Puig, and J M García-Marques, and J M de Moragas
May 2020, Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG,
R M Pujol, and L Puig, and J M García-Marques, and J M de Moragas
July 2012, Indian journal of dermatology,
Copied contents to your clipboard!