Five adults who suffered from eczema for at least five years were treated in a multiple baseline design with EMG biofeedback and progressive relaxation. Treatment consisted of five weekly EMG training sessions combined with regular home practice of relaxation. Three dependent measures were used to assess treatment effects: (1) daily self-monitoring of symptom irritation levels, (2) pre and post assessments of eczema affected areas and (3) the Spielberger Trait Anxiety Questionnaire which was also administered on a pre-post basis. Results showed clinically meaningful improvements in all five participants which were maintained at a two month follow-up. A second follow-up two years later showed that three of subjects were asymptomatic. The other two subjects could not be located. Taken together, the study provides evidence that EMG biofeedback combined with home practice of progressive relaxation can help to reduce the severity of eczema and the irritation associated with the disorder.