Fructose Consumption and Lipid Metabolism in Obese Children and Adolescents. 2019

Aneta Czerwonogrodzka-Senczyna, and Małgorzata Rumińska, and Anna Majcher, and Dominika Credo, and Anna Jeznach-Steinhagen, and Beata Pyrżak
Department of Clinical Dietetics, Warsaw Medical University Warsaw, Warsaw, Poland. aneta.czerwonogrodzka@wum.edu.pl.

Inappropriate dietary habits influence the development of excessive body weight. The role of added sugars, including fructose, notably is significant in this process. It is estimated that fructose intake has increased many times over the past two centuries. The aim of the study was to define the effect of fructose consumption on anthropometric indices and lipid metabolism in obese (body mass index (BMI) >30 kg/m2) children and adolescents. The study included 84 patients (47 girls and 37 boys) aged 7-18 years, divided into prepubertal, pubertal, and post-pubertal age groups. Aside from BMI, the assessment comprised waist circumference, body composition estimated with bioelectrical impedance (BIA), plasma lipid profile, fructose intake consumption based on a 3-day menu analysis, and a number of calculated atherogenic indices. The major findings were that total daily fructose intake was high, on average, ranging from 19 to 26 g, with no appreciable relation to age. A higher fructose intake from beverages is significantly associated with the percentage of body fat, waist circumference, waist-to-height ratio, and also with the content of total cholesterol, triglycerides, and the level of atherogenic indices. In conclusion, fructose appears a particularly unfavorable component in children's diet as it is conducive to visceral obesity and atherogenic lipid profile. However, inadequate proportions of other macronutrients may also be at play in the development of metabolic diet-related disorders.

UI MeSH Term Description Entries
D008297 Male Males
D009765 Obesity A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D005260 Female Females
D005632 Fructose A monosaccharide in sweet fruits and honey that is soluble in water, alcohol, or ether. It is used as a preservative and an intravenous infusion in parenteral feeding. Levulose,Apir Levulosa,Fleboplast Levulosa,Levulosa,Levulosa Baxter,Levulosa Braun,Levulosa Grifols,Levulosa Ibys,Levulosa Ife,Levulosa Mein,Levulosado Bieffe Medit,Levulosado Braun,Levulosado Vitulia,Plast Apyr Levulosa Mein,Levulosa, Apir,Levulosa, Fleboplast
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D015992 Body Mass Index An indicator of body density as determined by the relationship of BODY WEIGHT to BODY HEIGHT. BMI Quetelet Index,Quetelet's Index,Index, Body Mass,Index, Quetelet,Quetelets Index
D050356 Lipid Metabolism Physiological processes in biosynthesis (anabolism) and degradation (catabolism) of LIPIDS. Metabolism, Lipid
D055105 Waist Circumference The measurement around the body at the level of the ABDOMEN and just above the hip bone. The measurement is usually taken immediately after exhalation. Circumference, Waist,Circumferences, Waist,Waist Circumferences

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