In this work, sulfochlorinated polysulfone (SC-PSf), a functional polysulfone with chlorine resistance, was synthesized through metalation sulfochlorination of polysulfone (PSf). For endowing the required hydrophilicity of SC-PSf, the sulfonyl chloride groups on SC-PSf were partially hydrolyzed to sulfonic groups to produce sulfonated SC-PSf (SC-S-PSf). Thin film composite (TFC) membranes for reverse osmosis application were fabricated by coating solution of SC-S-PSf on porous PSf substrate and then crosslinked by piperazine (PIP) to form polysulfone-sulfamide (PSSA) skin layer. In order to enhance the spreadability of polymer solution on PSf supporting layer, tetrabutylammonium chloride (TBAC), a common surfactant, was added into the coating solution. A flawless membrane was acquired only by a single coating step and at dilute SC-S-PSf solution when TBAC was added into polymer solution. Through optimizing coating conditions, the NaCl rejection and water flux of PSSA membrane reached 96.9% and 17.8 L/m2h under brackish desalination conditions. Moreover, the PSSA membrane exhibited the long-term stability against chlorine during the operation condition of 2000 ppm NaOCl for 10 days. The salt rejection of PSSA only decreased by 1%. In contrast, the salt rejection of polyamide membrane decreased by 8% under the same condition.