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Nineteen compounds, including kihadanin D (1), obacunone (2), kihadanin A (3), kihadanin B (4), kihadanin C (5), limonin (6), evodol (7), fraxinellone (8), furo[2,3-b]quinolin-4-ol (9), preskimmianine (10), ifflaiamine (11), dictamnol (12), naringenin (13), diosmetin (14), wogonin (15), scopoletin (16), cleomiscosin A (17), apocynin (18), and methyl pyroglutamate (19), were isolated from the methanol extract of the root barks of Dictamnus dasycarpus by using various column chromatographies. Their chemical structures were extensively determined on basis of UV, IR, NMR, MS, and CD spectroscopic data analyses. Among them, 1 is a new limonoid, 9 was isolated from plant kingdom for the first time, 11, 13-14 and 17-19 were obtained from the genus Dictamnnus for the first time. Cytotoxicities of compounds 1-18 were tested, and the results indicated that 1 exhibited cytotoxicities against three human cancer cell lines MDA-MB-231, A549 and HT29 with IC₅₈ values of 16.22, 21.72 and 31.06 μmol·L⁻¹, respectively.
Xi-Xi Guo, and
Li-Na Zhao, and
Jia Wang, and
Shuai Liu, and
Qi-Rui Bi, and
Zhe Wang, and
Ning-Hua Tan
February 2014,
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials,
Xi-Xi Guo, and
Li-Na Zhao, and
Jia Wang, and
Shuai Liu, and
Qi-Rui Bi, and
Zhe Wang, and
Ning-Hua Tan
September 1992,
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica,
Xi-Xi Guo, and
Li-Na Zhao, and
Jia Wang, and
Shuai Liu, and
Qi-Rui Bi, and
Zhe Wang, and
Ning-Hua Tan
November 2005,
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica,
Xi-Xi Guo, and
Li-Na Zhao, and
Jia Wang, and
Shuai Liu, and
Qi-Rui Bi, and
Zhe Wang, and
Ning-Hua Tan
May 2002,
Planta medica,
Xi-Xi Guo, and
Li-Na Zhao, and
Jia Wang, and
Shuai Liu, and
Qi-Rui Bi, and
Zhe Wang, and
Ning-Hua Tan
August 2012,
Journal of enzyme inhibition and medicinal chemistry,
Xi-Xi Guo, and
Li-Na Zhao, and
Jia Wang, and
Shuai Liu, and
Qi-Rui Bi, and
Zhe Wang, and
Ning-Hua Tan
January 2010,
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica,
Xi-Xi Guo, and
Li-Na Zhao, and
Jia Wang, and
Shuai Liu, and
Qi-Rui Bi, and
Zhe Wang, and
Ning-Hua Tan
May 2022,
Journal of Asian natural products research,
Xi-Xi Guo, and
Li-Na Zhao, and
Jia Wang, and
Shuai Liu, and
Qi-Rui Bi, and
Zhe Wang, and
Ning-Hua Tan
August 2010,
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica,
Xi-Xi Guo, and
Li-Na Zhao, and
Jia Wang, and
Shuai Liu, and
Qi-Rui Bi, and
Zhe Wang, and
Ning-Hua Tan
July 2007,
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica,
Xi-Xi Guo, and
Li-Na Zhao, and
Jia Wang, and
Shuai Liu, and
Qi-Rui Bi, and
Zhe Wang, and
Ning-Hua Tan
November 2022,
Fitoterapia,
