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Efficient two-step synthesis of structurally diverse indolo[2,3-b]quinoline derivatives. 2019

Sandip Kundal, and Baitan Chakraborty, and Kartick Paul, and Umasish Jana
Department of Chemistry, Jadavpur University, Kolkata 700032, West Bengal, India. jumasish2004@yahoo.co.in umasish@gmail.com.

A general and efficient synthesis of diverse tetracyclic indolo[2,3-b]quinoline derivatives was achieved through palladium-catalyzed domino carboannulation/cross-coupling and DDQ-mediated double cross-dehydrogenative C-N bond formation. This approach provides a straightforward, atom-economical and concise route to easily access a diverse range of tetracyclic indolo[2,3-b]quinolines and their analogues in excellent yields with good tolerance of functional groups.

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