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Changes in androgen binding protein (ABP) production following continuous low dose gamma irradiation (IR) of adult rat. 1988
P Kamtchouing, and
G Pinon-Lataillade, and
V Papadopoulos, and
M A Drosdowsky, and
M T Hochereau de Reviers, and
S Carreau
Department of Biochemistry, UA CNRS 609, CHU 14033 Caen, France.
Continuous low dose gamma irradiation induces a progressive degeneration of germ cells with a concomittant increase in blood FSH; however, the Sertoli cell function is not too much altered since serum ABP level is normal and it is likely that the decrease of epididymal ABP content is the consequence of a reduction in seminiferous tubule fluid excretion. Obviously, spermatids seems to be involved in the regulation of Sertoli cell ABP synthesis.
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