BIOMAT Database Logo BIOMAT Database Logo

Low insulin response: a marker of prediabetes. 1988

S Efendic, and V Grill, and R Luft, and A Wajngot
Department of Endocrinology, Karolinska Hospital, Stockholm, Sweden.

UI MeSH Term Description Entries
D007328 Insulin A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1). Iletin,Insulin A Chain,Insulin B Chain,Insulin, Regular,Novolin,Sodium Insulin,Soluble Insulin,Chain, Insulin B,Insulin, Sodium,Insulin, Soluble,Regular Insulin
D011236 Prediabetic State The time period before the development of symptomatic diabetes. For example, certain risk factors can be observed in subjects who subsequently develop INSULIN RESISTANCE as in type 2 diabetes (DIABETES MELLITUS, TYPE 2). Prediabetes,Prediabetic States,State, Prediabetic,States, Prediabetic
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D011254 Pregnancy in Diabetics The state of PREGNANCY in women with DIABETES MELLITUS. This does not include either symptomatic diabetes or GLUCOSE INTOLERANCE induced by pregnancy (DIABETES, GESTATIONAL) which resolves at the end of pregnancy. Pregnancy in Diabetes,Pregnancy in Diabete,Pregnancy in Diabetic
D001786 Blood Glucose Glucose in blood. Blood Sugar,Glucose, Blood,Sugar, Blood
D003924 Diabetes Mellitus, Type 2 A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY. Diabetes Mellitus, Adult-Onset,Diabetes Mellitus, Ketosis-Resistant,Diabetes Mellitus, Maturity-Onset,Diabetes Mellitus, Non-Insulin-Dependent,Diabetes Mellitus, Slow-Onset,Diabetes Mellitus, Stable,MODY,Maturity-Onset Diabetes Mellitus,NIDDM,Diabetes Mellitus, Non Insulin Dependent,Diabetes Mellitus, Noninsulin Dependent,Diabetes Mellitus, Noninsulin-Dependent,Diabetes Mellitus, Type II,Maturity-Onset Diabetes,Noninsulin-Dependent Diabetes Mellitus,Type 2 Diabetes,Type 2 Diabetes Mellitus,Adult-Onset Diabetes Mellitus,Diabetes Mellitus, Adult Onset,Diabetes Mellitus, Ketosis Resistant,Diabetes Mellitus, Maturity Onset,Diabetes Mellitus, Slow Onset,Diabetes, Maturity-Onset,Diabetes, Type 2,Ketosis-Resistant Diabetes Mellitus,Maturity Onset Diabetes,Maturity Onset Diabetes Mellitus,Non-Insulin-Dependent Diabetes Mellitus,Noninsulin Dependent Diabetes Mellitus,Slow-Onset Diabetes Mellitus,Stable Diabetes Mellitus
D005260 Female Females
D005500 Follow-Up Studies Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease. Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D005951 Glucose Tolerance Test A test to determine the ability of an individual to maintain HOMEOSTASIS of BLOOD GLUCOSE. It includes measuring blood glucose levels in a fasting state, and at prescribed intervals before and after oral glucose intake (75 or 100 g) or intravenous infusion (0.5 g/kg). Intravenous Glucose Tolerance,Intravenous Glucose Tolerance Test,OGTT,Oral Glucose Tolerance,Oral Glucose Tolerance Test,Glucose Tolerance Tests,Glucose Tolerance, Oral
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

S Efendic, and V Grill, and R Luft, and A Wajngot
Is a low insulin response to intravenous glucose a marker of type 1 (insulin-dependent) insulin?
February 1989, Diabetologia,
S Efendic, and V Grill, and R Luft, and A Wajngot
The regulation of splanchnic glucose production in subjects with low insulin response--a compensatory mechanism in prediabetes?
May 1973, European journal of clinical investigation,
S Efendic, and V Grill, and R Luft, and A Wajngot
Diminished insulin response to hyperglycemia in prediabetes and diabetes.
August 1967, Diabetes,
S Efendic, and V Grill, and R Luft, and A Wajngot
Low acute insulin response to intravenous glucose. A sensitive but non-specific marker of early stages of type 1 (insulin-dependent) diabetes.
August 1988, Diabetologia,
S Efendic, and V Grill, and R Luft, and A Wajngot
Insulin and growth hormone secretion stimulated by intravenous administration of arginine in the low insulin responders (prediabetes?).
December 1977, The Tohoku journal of experimental medicine,
S Efendic, and V Grill, and R Luft, and A Wajngot
Insulin response in bulimia nervosa as a marker of nutritional depletion.
November 1996, The International journal of eating disorders,
S Efendic, and V Grill, and R Luft, and A Wajngot
Follow-up of GK rats during prediabetes highlights increased insulin action and fat deposition despite low insulin secretion.
January 2008, American journal of physiology. Endocrinology and metabolism,
S Efendic, and V Grill, and R Luft, and A Wajngot
The in vivo visualization of insulitis. A new marker of prediabetes.
January 1988, Advances in experimental medicine and biology,
S Efendic, and V Grill, and R Luft, and A Wajngot
Metabolic Syndrome: Insulin Resistance and Prediabetes.
August 2015, FP essentials,
S Efendic, and V Grill, and R Luft, and A Wajngot
Identifying prediabetes using fasting insulin levels.
January 2010, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists,
Copied contents to your clipboard!