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The aim of our work was the search for immunogenetic factors that influence the antibody response to HBs antigen. We analyzed the HLA-A, -B, and -DR antigen frequencies in 19 seropositive to HBs and 28 seronegative to HBs healthy persons finding an elevated frequency of B5 in the seropositive group (p value 0.037). After vaccination with Hevac B Pasteur vaccine of the seronegative persons, the low antibody response was associated with B13 (p value 0.041). An association between local side reactions to the vaccine and HLA A3 and B35 were also found (p values 0.042 and 0.022 respectively). The presented p values are not significant after correction for the number of antigens tested and for this reason our findings require confirmation in an independent study.
H Matej, and
B Nowakowska, and
J Pacyńska, and
A Gładysz, and
M Zalewska, and
K Simon
July 1997,
Tissue antigens,
H Matej, and
B Nowakowska, and
J Pacyńska, and
A Gładysz, and
M Zalewska, and
K Simon
May 1990,
British journal of industrial medicine,
H Matej, and
B Nowakowska, and
J Pacyńska, and
A Gładysz, and
M Zalewska, and
K Simon
January 1993,
Vaccine,
H Matej, and
B Nowakowska, and
J Pacyńska, and
A Gładysz, and
M Zalewska, and
K Simon
August 2012,
Sleep,
H Matej, and
B Nowakowska, and
J Pacyńska, and
A Gładysz, and
M Zalewska, and
K Simon
September 1986,
Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology,
H Matej, and
B Nowakowska, and
J Pacyńska, and
A Gładysz, and
M Zalewska, and
K Simon
August 1985,
Annals of internal medicine,
H Matej, and
B Nowakowska, and
J Pacyńska, and
A Gładysz, and
M Zalewska, and
K Simon
August 1988,
JAMA,
H Matej, and
B Nowakowska, and
J Pacyńska, and
A Gładysz, and
M Zalewska, and
K Simon
June 1998,
Kidney international,
H Matej, and
B Nowakowska, and
J Pacyńska, and
A Gładysz, and
M Zalewska, and
K Simon
October 1997,
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association,
H Matej, and
B Nowakowska, and
J Pacyńska, and
A Gładysz, and
M Zalewska, and
K Simon
May 2006,
Brain, behavior, and immunity,
