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Portal Vein Thrombosis in a Patient with Hereditary Antithrombin Deficiency. 2019
Tamao Setaka, and
Katsuharu Hirano, and
Keiichi Moriya, and
Tougen Kaneko, and
Seie Morita, and
Tetsu Shinkai, and
Eriko Morishita, and
Takafumi Ichida
Department of Internal Medicine, Shonan East General Hospital, Japan.
Portal vein thrombosis (PVT) has been reported in many patients with and without liver cirrhosis. The portal vein is a rare site of thrombosis, and various conditions can predispose an individual to PVT. Among those conditions, hereditary thrombophilia has been increasingly reported recently. We herein report the case of a non-cirrhotic 30-year-old man who developed acute PVT with hereditary antithrombin deficiency. Antithrombin (AT) replacement therapy was required along with heparin. Given our experience with this case, we believe that a screening test for prothrombotic disorders, such as AT deficiency, should be considered in cases of PVT.
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