Hydrolysis of 2-Chloroethyl Palmitate and 2-Chloroethyl Linoleate by Mammalian Enzymes. 1981

John J Sullivan, and John J Majnarich
BioMed Research Laboratories, 1115 East Pike Street, Seattle, Washington 98122.

Hydrolysis of 2-chloroethyl palmitate and 2-chloroethyl linoleate was studied in artificial gastric juice, artificial pancreatic juice, pig liver homogenates and pig intestine homogenates. Hydrolytic activity was followed by gas-liquid chromatography. Substantial hydrolysis was observed in all preparations except the artificial gastric juice. Hydrolysis constants ranged from <0.001 min-1 in the gastric juice to 0.064 min-1 for the linoleate ester in the pancreatic juice.

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